The laboratory of Dr. Wonho Kim at the University of North Carolina at Chapel Hill is seeking a highly motivated postdoctoral fellow. Our lab investigates the molecular mechanisms by which the genome is organized in three-dimensional space and how this spatial organization influences nuclear functions such as gene transcription, DNA replication, and DNA damage response. To address these questions, we combine diverse approaches including genomics (Hi-C, ChIP-seq), DNA-FISH, biochemical assays, and genetic screening.

For more information, please visit our lab website:
https://sites.google.com/view/wonhokimlab/home

Representative publications:
1) A Genetic Screen for Modifiers of Cohesin Clustering Identifies Regulators of Genome Folding (Science Advances, 2026):
https://www.science.org/doi/10.1126/sciadv.adx5130
2) BRD4 orchestrates genome folding to promote neural crest differentiation (Nature Genetics, 2021):
https://www.nature.com/articles/s41588-021-00934-8

What You’ll Do
1) Lead an independent project on the regulatory mechanisms of cohesin-mediated genome folding.
2) Design and execute rigorous experiments; analyze, interpret, and present findings; and prepare manuscripts under supervision.
3) Contribute to a supportive lab culture and mentor junior trainees.

What You Bring
1) PhD or MD (or near completion).
2) Strong motivation; excellent experimental and communication skills.
3) Demonstrated research productivity (at least one peer-reviewed publication or preprint)
4) Research experience in epigenetics and chromatin biology is preferred but not required.

Why Join Us
1) Direct, personalized mentorship toward your career goals.
2) Access to state-of-the-art core facilities at UNC.
3) A collaborative environment that values innovation and scientific rigor.

How to apply
Interested candidates should send the following materials to [email protected]
1) Cover letter describing your research experience, interests, and career goals.
2) CV including contact information for three references.