The Cleveland Clinic is establishing an innovative Center for Experimental Therapeutics whose vision is to be at the forefront of drug discovery and development. The Center is committed to pioneering new approaches that leverage cutting-edge technologies and accelerate the creation of novel therapeutics that address unmet medical needs. It is supported by the exceptional resources at the Cleveland Clinic.

We are seeking a highly motivated faculty member to join our dynamic team. The ideal candidate will have expertise in AI-based drug discovery (such as small molecules and biologics) and testing. This is a unique growth opportunity to join a top-ranked medical center and contribute to groundbreaking research at the intersection of artificial intelligence and therapeutic innovation.

Key Responsibilities:

• Develop and apply AI/ML models in multiple areas of therapeutic development including novel target identification as well as prediction and design of novel therapeutic biologics (such as antibodies and nanobodies) and/or small molecule compounds.
• Collaborate with interdisciplinary teams to integrate computational approaches with experimental validation.
• Secure research funding and lead projects in AI-driven drug discovery.
• Mentor graduate students and postdoctoral fellows, fostering a collaborative and innovative research environment.
• Publish high-impact research findings in peer-reviewed journals and present at scientific conferences.

Qualifications:

• PhD. and/or M.D.(orequivalent in Computational Biology, Bioinformatics, Computer Science, Chemistry, or a related field.
• Demonstrated expertise in AI and machine learning techniques (such as deep learning, generative AI, foundation models) as applied to drug discovery.
• Strong publication record showcasing innovative research in AI and therapeutics.
• Excellent communication and teamwork skills, with a commitment to interdisciplinary collaboration.
• Experience in securing research funding and leading research projects is desirable.

What We Offer:

• Access to state-of-the-art facilities and resources within a collaborative research environment at Cleveland Clinic.
• Opportunities for professional growth and development in a leading academic institution.
• Competitive salary and benefits package.

Cleveland Clinic

Cleveland Clinic has operated for over 100 years on the principle of bringing innovative teams together to advance patient care. Today, we are a world leader in science-based healthcare. Our strategic plan for research harnesses information technology to power significant advances in both personalized and population medicine. A major component of our strategy includes our anchor role in building the Cleveland Innovation District. This unprecedented collaboration includes participation and investment by the State of Ohio, along with five independent Cleveland healthcare and academic institutions and is designed to transform research, education, and economic opportunities in Northeast Ohio, the United States, and across the world.

Cleveland Clinic Research

Cleveland Clinic Research, a part of the global Cleveland Clinic enterprise, has a footprint spanning nearly 1 million square feet, with two new state-of-the-art facilities scheduled to open in 2026. In 2024, research funding grew to $520 million, which includes $176 million in federal funding across 632 federal awards. In addition, Cleveland Clinic's global footprint provides a wealth of resources to support research throughout the enterprise, including our locations in Northeast Ohio, Florida, London, and Abu Dhabi.

Application Instructions:

Interested candidates should submit the following to Kelsey Garcia, [email protected]:

• A cover letter detailing your research interests and career goals.
• A curriculum vitae (CV).
• A statement of research plans (2-3 pages).
• Contact information for three professional references.

About Cleveland Clinic

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Cleveland Clinic's vision is to become the best place for care and the best place to work in healthcare.We are committed to providing a safe, stable, and financially fulfilling work environment. Cleveland Clinic is ambitiously investing in growth. Being a physician-led organization means doing what is best for the patients, every day.

Cleveland Clinic is one of the world's largest and busiest health centers. Patients come to Cleveland Clinic from all over the world. We offer advanced treatment for all illnesses and disorders of the body.

Cleveland Clinic is a nonprofit, multispecialty academic medical center that's recognized in the U.S. and throughout the world for its expertise and care. Cleveland Clinic integrates clinical and hospital care with research and education. Located in Cleveland, Ohio, it was founded in 1921 by four renowned physicians with a vision of providing outstanding patient care based upon the principles of cooperation, compassion and innovation. Cleveland Clinic has pioneered many medical breakthroughs, including coronary artery bypass surgery and the first face transplant in the United States. U.S. News & World Report consistently names Cleveland Clinic as one of the nation's best hospitals in its annual America's Best Hospitals survey. Among Cleveland Clinic's 80,642 employees worldwide are more than 5,743 salaried physicians and researchers, and 20,166 registered nurses and advanced practice providers, representing 140 medical specialties and subspecialties. Cleveland Clinic is a 6,690-bed health system that includes a 173-acre main campus near downtown Cleveland, 23 hospitals, more than 270 outpatient facilities, including locations in northeast Ohio; southeast Florida; Las Vegas, Nevada; Toronto, Canada; Abu Dhabi, UAE; and London, England. In 2024, there were 14.1 million total outpatient visits, 333,000 hospital admissions and observations, and 320,000 surgical cases throughout Cleveland Clinic's health system. Patients came for treatment from every state and 185 countries.

Cleveland Clinic is pleased to be an equal employment opportunity employer. Smoke/drug free environment.

Any application submitted without a CV will delay the review process

Please be advised that all information entered in your application will only be shared with Cleveland Clinic and will not be distributed to third parties.

The pay range displayed on this job posting reflects the anticipated range for new hires and is for a 100%, full-time employment (FTE). A successful candidate's actual compensation will be consistent with fair market value and determined after taking various factors into consideration such as the candidate's work history, experience, skill set, % of FTEand board certification. This is not inclusive of the value of Cleveland Clinic's benefits package, which includes among other benefits, healthcare/dental/vision, and retirement.

Cleveland is part of Northeast Ohio which is composed of six metropolitan areas. Each of them provides affordable real estate, excellent schools, safe communities as well as an abundance of outdoor activities. Find out herehow great it is to live in Cleveland!

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