Under the general supervision of an Associate Study Director/Study Director/Senior Study Director, the incumbent is responsible for production of humanized mice, maintaining accurate inventory, conducting a variety of product development research efforts including optimizing human immune function in humanized mice, engraftment kinetics and humanized liver. Solid or liquid patient derived tumor modeling in immune deficient variant mouse strains. Makes detailed observations, analyzes data and interprets results. Keeps excellent data records and easy retrieval to fulfill client data requests. Ensures the experimental protocols are compliant with animal welfare and are faithfully transferred to the Operation team for consistency in product offerings. Individual Research Associates will be a collaborative member of the cross functional In Vivo department and are assigned to work within the Operations team. The incumbent ensures prompt communication with the client, a successful transfer of studies into the lab and the execution of studies with the highest quality and with scientific integrity. In addition, the incumbent is responsible for ensuring the accuracy of AXAPTA and LIMS entries.

The salary range is $64,001 - $92,802. Salary will be determined based on qualifications and experience

Key Responsibilities & Essential Functions:

• Contributes to the technical design of experiments and methods, develops conclusions, and makes recommendations for further action.
• Frequently designs novel methodology for solving tactical problems.
• Conducts varied and complex experiments requiring high-level technical skills. Anticipates challenges and is able to troubleshoot common technical issues, and plan for alternatives.
• Performs complex laboratory techniques such as cell culture, flow cytometry, standard cellular and molecular, and in vivo pharmacology solid and liquid tumor xenograft biology experiments with a significant amount of independence. Collects and analyzes data and interprets results.
• Prepares detailed written and oral presentations of data, results, and conclusions, concisely and confidently.
• Maintains laboratory notebook and electronic LIMS data. Documents experimental results and procedures clearly and concisely in required format.
• Improves experimental procedures if necessary through discussion with internal and external investigators.
• Provide mentoring to technicians, technical guidance and scientific support.
• Ensures AUC protocols and/or amendments are in place and are accurate relative to the statement of work and submitted memos prior to study initiation.
• Ensure the studies and projects are executed per statement of work without deviation.
• In collaboration with Associate Study Director/Study Director/Senior Study Director, drive process improvement on study execution leading to better workforce utilization, improved processes, enhanced turnaround times, and improved lead-times for study initiation.
• Ensures the experimental protocols are faithfully transferred to the Operation team for consistency in product offerings.

Minimum Qualifications:

• Bachelor’s degree with at least 5 years of relevant work experience within an advanced biosciences research laboratory.
• Must be knowledgeable in advanced cell culture techniques, cell isolation and characterization techniques; flow cytometry techniques and flow data analysis.
• Excellent interpersonal skills to execute tasks in a collaborative environment.
• Must be able to establish two-way communication with collaborators, technicians and department heads regarding specific needs and deadlines.
• Strong proficiency with a variety of software tools including Microsoft Office, GraphPad, and FlowJo.
• Exceptional problem solving skills and ability to resolve technical issues independently and in a timely manner. Excellent organizational and time management skills and the ability to pay attention to detail while multi-tasking in a fast paced work environment.

About JAX:

The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.

Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit www.jax.org​​​​​​​.