The Benoit lab at the University of Ottawa has a Postdoctoral Fellow position available to study human colorectal cancer and develop future therapeutic strategies to target cancer stem cells. The overarching goal of the Benoit lab is to develop new anticancer agents targeting essential elements of human colon cancer stem cell chromatin organization. The research led by the candidate will utilize patient-derived tissues, high-content imaging, organoid-based 3D bioprinting systems, high-throughput drug screening, genome-editing tools, and in vivo tumorigenesis models to evaluate the impact of small molecules on epigenetic regulation mechanisms essential to neoplastic stemness. The candidate will also work with bulk, spatial, and single-cell genomic analyses, spectral flow cytometry, and single-cell proteomics.
This position offers a unique opportunity for professional growth and development in a collaborative and dynamic research environment. We offer competitive salary and benefits package, with the possibility to renew/extend based on performance.‍

Published research work by the Benoit lab is found here:
https://pubmed.ncbi.nlm.nih.gov/?term=Benoit%20YD%20Ottawa&sort=date

Qualifications:

The position is for a PhD or MD/PhD holder, who graduated from a highly recognized academic program.
A strong background in cancer and/or stem cell biology is required. Advanced skills in cellular imaging, molecular biology, flow cytometry, mammalian cell culture, in vivo models, and genomic data analysis are highly desirable. Priority will be given to candidates with demonstrated computational biology knowledge and proficiency (Proficiency in data analysis using R or Python).

Ability to work independently, show self-initiative and attention to detail, and motivation to explore new techniques and concepts are essential.

Publication of relevant research work in recognized scientific journals is an asset.

Outstanding written and oral communication skills, team spirit, and adherence to highest ethical principles when collecting experimental data and working with laboratory animals are necessary.

Candidates can expect a positive, competitive, and success-oriented work environment, tailored to their personal career and publications goals. The successful candidate will engage in vibrant scientific discourse with the University of Ottawa molecular sciences and stem cell biologist community. Regular meetings with the PI will assure mutual expectations are met.

Only shortlisted candidates will be contacted.