Postdoctoral Fellow – Genetic and Chemical Screening for Therapeutic Discovery Using Human Organ Chips
- The Wyss Institute for Biologically Inspired Engineering at Harvard University
- Location: Boston, MA
- Job Number: 7205738
- Posting Date: Jan 9, 2024
- Application Deadline: Open Until Filled
Job Description
About the Wyss
The mission of the Wyss Institute for Biologically Inspired Engineering at Harvard University is to transform human healthcare and the environment by emulating the way nature builds. Developed as an alliance between Harvard and other premier academic and clinical partner institutions, Institute faculty and staff collaborate in high-risk, fundamental research and science-driven technology development. A major focus of the Institute is to translate the technologies developed by its faculty and staff into commercial products and therapies through collaborations with clinical investigators and establishment of corporate alliances. For more information, discover our technologies, catch up on our recent news, or watch our latest videos.
Role description
The Ingber lab is seeking a postdoctoral fellow to drive a discovery effort that combines genetic and small molecule screening with human Organ Chips. The goal is to identify therapeutic targets and/or drugs that mitigate injury and accelerate healing after ionizing radiation exposure. While effective radiation countermeasures are needed for medical and military defense situations, there are few FDA-approved drugs for this indication and we are aiming to add to that list. This is a key role in a fast-paced multi-year translational and collaborative project that spans the lung, intestine, bone marrow, and immune Organ Chips.
What you’ll need
-PhD (or MD PhD) in biology, chemical biology, or medicine-related field
-Prior experience executing genetic screens (e.g., pooled CRISPR or shRNA based) or small molecule screens for a biologic readout
-Demonstrated scientific productivity (peer-reviewed publications, presentations, and/or grants)
-Willingness to take initiative to help the team do exciting science and reach common goals
Preferred qualifications
-Primary human cell culture expertise (epithelial or hematopoietic/immune cells)
-Flow cytometry experience
-Availability to start within the first quarter of 2024
Benefits and Perks
-Medical/Dental/Vision: We offer a variety of excellent medical, dental, & vision plans. All coverage begins as of your start date.
-Time Off: 20 days of vacation per year
-Tuition Assistance Program: Competitive tuition assistance program, classes at the Harvard Extension School and discounted options through participating Harvard grad schools.
-Transportation: Harvard offers a 50% discounted MBTA pass as well as additional options to assist employees in their daily commute.
-Wellness Options: Harvard offers programs and classes at little or no cost, including stress management, nutrition, meditation, and complimentary health services.
Where You Can Apply
Applications, assembled as single PDF files, should contain a complete resume, cover letter describing research interests and goals, full list of publications, copies of up to three relevant scientific papers, as well as the names and contact information of three references. Applications should be sent to faculty_postdocs@wyss.harvard.edu using the subject line “Genetic and Chemical Screening”.
Harvard University is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law. Demonstrates a commitment to diversity, inclusion, and cultural awareness through actions, interactions, and communications with others.
https://wyss.harvard.edu/job/postdoctoral-fellow-genetic-and-chemical-screening-for-therapeutic-discovery-using-human-organ-chips/
The mission of the Wyss Institute for Biologically Inspired Engineering at Harvard University is to transform human healthcare and the environment by emulating the way nature builds. Developed as an alliance between Harvard and other premier academic and clinical partner institutions, Institute faculty and staff collaborate in high-risk, fundamental research and science-driven technology development. A major focus of the Institute is to translate the technologies developed by its faculty and staff into commercial products and therapies through collaborations with clinical investigators and establishment of corporate alliances. For more information, discover our technologies, catch up on our recent news, or watch our latest videos.
Role description
The Ingber lab is seeking a postdoctoral fellow to drive a discovery effort that combines genetic and small molecule screening with human Organ Chips. The goal is to identify therapeutic targets and/or drugs that mitigate injury and accelerate healing after ionizing radiation exposure. While effective radiation countermeasures are needed for medical and military defense situations, there are few FDA-approved drugs for this indication and we are aiming to add to that list. This is a key role in a fast-paced multi-year translational and collaborative project that spans the lung, intestine, bone marrow, and immune Organ Chips.
What you’ll need
-PhD (or MD PhD) in biology, chemical biology, or medicine-related field
-Prior experience executing genetic screens (e.g., pooled CRISPR or shRNA based) or small molecule screens for a biologic readout
-Demonstrated scientific productivity (peer-reviewed publications, presentations, and/or grants)
-Willingness to take initiative to help the team do exciting science and reach common goals
Preferred qualifications
-Primary human cell culture expertise (epithelial or hematopoietic/immune cells)
-Flow cytometry experience
-Availability to start within the first quarter of 2024
Benefits and Perks
-Medical/Dental/Vision: We offer a variety of excellent medical, dental, & vision plans. All coverage begins as of your start date.
-Time Off: 20 days of vacation per year
-Tuition Assistance Program: Competitive tuition assistance program, classes at the Harvard Extension School and discounted options through participating Harvard grad schools.
-Transportation: Harvard offers a 50% discounted MBTA pass as well as additional options to assist employees in their daily commute.
-Wellness Options: Harvard offers programs and classes at little or no cost, including stress management, nutrition, meditation, and complimentary health services.
Where You Can Apply
Applications, assembled as single PDF files, should contain a complete resume, cover letter describing research interests and goals, full list of publications, copies of up to three relevant scientific papers, as well as the names and contact information of three references. Applications should be sent to faculty_postdocs@wyss.harvard.edu using the subject line “Genetic and Chemical Screening”.
Harvard University is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law. Demonstrates a commitment to diversity, inclusion, and cultural awareness through actions, interactions, and communications with others.
https://wyss.harvard.edu/job/postdoctoral-fellow-genetic-and-chemical-screening-for-therapeutic-discovery-using-human-organ-chips/
