Research Scientist/Microsurgeon
- University of Missouri, Columbia
- Location: Columbia, MO
- Job Number: 7194768 (Ref #: JOBID 49171)
- Posting Date: Nov 17, 2023
- Salary / Pay Rate: $60,000-80,000
- Application Deadline: Open Until Filled
Job Description
The Immunomodulation and Translational Research Program in the Department of Pediatrics, University of Missouri, Columbia, MO, is seeking a Research Scientist/Microsurgeon. This position will work within the research lab in the NextGen Precision Health Building. The program has developed various novel biologics and targeted delivery biomaterial platforms with demonstrated efficacy for tolerance induction to allogeneic bone marrow cells and islets for the treatment of diabetes.
Job Duties and Scope Include:
• Conduct studies using novel recombinant proteins to modulate the immune response to prevent cell, tissue, and solid organ graft rejection.
• Perform islet isolation, assessment of quality and function in vitro, and transplantation under the kidney capsule, intraportal, or gonadal fat pad.
• Participate in the generation and use of humanized mouse models to assess the efficacy of lead immunomodulatory protocols to prevent rejection of human islets or stem-cell-derived beta cells in humanized mice as a prelude to clinical translation.
• Immune monitoring using flow cytometry, immunohistochemistry, and confocal microscopy.
• Additional duties include preparation of scientific publications, assistance with grant applications, and providing technical and teaching/training support to graduate students, postdoctoral fellows, and technicians in the program.
100% On-site work.
Hiring Range: $60,000 – 80,000 annually
Work Hours: 40 hours/week
Minimum Qualifications:
• Ph.D., M.D., or D.V.M. Candidates with BSc or MS with extensive microsurgical skills will also be considered.
• A minimum of 3 years of experience in performing microsurgery in rodents with a focus on islet transplantation.
• Experience with the transplantation of solid organs, heart or kidney is highly desirable.
• Experience with immunohistochemistry.
Preferred Qualifications:
• Experience with multiparameter flow cytometry and immune cell functions, such as mixed lymphocyte reactions.
• Experience with DNA techniques and mammalian tissue culture.
• Effective oral and written and interpersonal communications skills as well as proficiency in word, excel, PowerPoint, and statistical software.
Please e-mail your curriculum vitae and list of three references with contact information to [email protected]
This position is eligible for University benefits. The University offers a comprehensive benefits package, including medical, dental and vision plans, retirement, and educational fee discounts.
For additional information on University benefits, please visit the Faculty & Staff Benefits website at http://www.umsystem.edu/totalrewards/benefits
Job Duties and Scope Include:
• Conduct studies using novel recombinant proteins to modulate the immune response to prevent cell, tissue, and solid organ graft rejection.
• Perform islet isolation, assessment of quality and function in vitro, and transplantation under the kidney capsule, intraportal, or gonadal fat pad.
• Participate in the generation and use of humanized mouse models to assess the efficacy of lead immunomodulatory protocols to prevent rejection of human islets or stem-cell-derived beta cells in humanized mice as a prelude to clinical translation.
• Immune monitoring using flow cytometry, immunohistochemistry, and confocal microscopy.
• Additional duties include preparation of scientific publications, assistance with grant applications, and providing technical and teaching/training support to graduate students, postdoctoral fellows, and technicians in the program.
100% On-site work.
Hiring Range: $60,000 – 80,000 annually
Work Hours: 40 hours/week
Minimum Qualifications:
• Ph.D., M.D., or D.V.M. Candidates with BSc or MS with extensive microsurgical skills will also be considered.
• A minimum of 3 years of experience in performing microsurgery in rodents with a focus on islet transplantation.
• Experience with the transplantation of solid organs, heart or kidney is highly desirable.
• Experience with immunohistochemistry.
Preferred Qualifications:
• Experience with multiparameter flow cytometry and immune cell functions, such as mixed lymphocyte reactions.
• Experience with DNA techniques and mammalian tissue culture.
• Effective oral and written and interpersonal communications skills as well as proficiency in word, excel, PowerPoint, and statistical software.
Please e-mail your curriculum vitae and list of three references with contact information to [email protected]
This position is eligible for University benefits. The University offers a comprehensive benefits package, including medical, dental and vision plans, retirement, and educational fee discounts.
For additional information on University benefits, please visit the Faculty & Staff Benefits website at http://www.umsystem.edu/totalrewards/benefits
