Postdoctoral Associate [Med-Medicine - (23005729)]
- University of Pittsburgh
- Location: Pennsylvania, Pittsburgh
- Job Number: 7191419 (Ref #: 23005729)
- Posting Date: Nov 4, 2023
A postdoctoral position is immediately available at the University of Pittsburgh School of Medicine's Renal-Electrolyte Division to study visceral mechanotransduction and nociception. Normal bladder function and nociceptive responses to bladder inflammation and injury depend on inputs from afferent nerve fibers located within the bladder mucosa and the underlying musculature. These afferent fibers express a myriad of ligand- and mechano-gated ion channels and receptors that convert chemical and mechanical stimuli into electrical signals. How this complex sensory information is processed and integrated into the afferents that innervate the urinary bladder remains unresolved.
The candidate will conduct critical bench experiments to define how acid-sensing ion channels (ASICs) and small conductance Ca2+-activated (SK) channels control bladder afferent outflow. The project involves the use of the following techniques: in situ hybridization, confocal imaging, ex vivo nerve recordings, patch clamp, and behavioral tests. Candidates should show a strong interest and motivation to develop new ideas towards the goals of the overall research program.
If the diploma has been not conferred, please provide a copy of the transcripts or a letter from the Program Director stating that the candidate has fulfilled all of their requirements and that their dissertation has been approved in final format. If revisions were requested, the candidate must complete the revisions and have the dissertation approved in final format before they can begin their postdoctoral training. If one of your requirements has not been yet completed, please have the Program Director include the date it will be completed within that letter.
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