Post Doctoral Fellow: Infectious Disease/Vaccine Research
- Location: Ridley Park, PA
- Job Number: 7182234
- Posting Date: Sep 25, 2023
- Application Deadline: Oct 25, 2023
Be a part of the legacy: Postdoctoral Research Fellow Program
Our Research Laboratories’ Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.
Our company is a global health care leader with a diversified portfolio of prescription medicines, vaccines, and consumer health products, as well as animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us.
Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity, and teamwork of people like you. To this end, we strive to create an environment of mutual respect, encouragement, and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.
Be a part of the legacy: our Manufacturing Division Postdoctoral Research Fellow Program
Our company's Research Laboratories Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.
We are seeking a talented and motivated candidate with expertise in immunology, vaccinology, or host-pathogen interaction and a strong interest in adaptive immunological memory to join the Infectious Disease & Vaccines: Immunology group at our company’s West Point, PA site. As a postdoctoral fellow in our Manufacturing Division Infectious Disease & Vaccines, you will work with a highly collaborative team of scientists across functional and therapeutic areas to investigate basic immunological mechanisms regulating vaccine durability. The successful candidate will be responsible for launching independent projects that interrogate how decisions made during vaccine design impact the development of immunological memory, with a primary focus on the development of long-lived plasma cells and memory B cells. The postdoctoral fellow will collaborate closely with a mentor to develop research plans, enable model development, conduct mechanistic studies, and generate novel insights which can be leveraged to generate more durable vaccine responses.
Responsibilities include but are not limited to:
Establishment and optimization of vaccine models in pre-clinical animal species.
Development of immunological assays to characterize antigen-specific humoral and cellular immune responses.
Performing single cell assays including high-parameter flow cytometry and single cell omics profiling (e.g. single cell RNAseq, BCRseq, and ATACseq).
Data interpretation, manuscript and patent preparation, publication, and presentation
Education Minimum Requirement:
Must have a Ph.D. in Immunology, Vaccinology, Host-Pathogen Interaction, or related field or will complete your PhD within the next year. Must have 3 years or less of postdoctoral experience.
Required Experience and Skills:
Expertise in the in vivo development of adaptive immunological memory.
Hands-on experience working with pre-clinical animal models and manipulating samples derived from these models.
Hands-on experience and solid knowledge in aseptic techniques in tissue culture.
Hands-on experience and solid knowledge in molecular biology.
Hands-on experience with in vitro assay development and troubleshooting.
Experience in immunological assays (e.g. ELISA, ELISPOT, high-parameter flow cytometry, cell sorting, in vitro restimulation assays).
Strong publication record and ability to design and execute experiments and interpret data.
Excellent communication and collaboration skills.
Skills that would be a plus but not required:
Expertise in B cell differentiation and B cell responses to vaccination or infection.
Familiarity with BSL2 level viral pathogens (e.g. SARS-CoV2, RSV, etc.)
Familiarity or experience with single-cell omics assays and data analysis.
Familiarity or experience with BCR repertoire sequencing and analysis.
Familiarity or experience with novel vaccine adjuvants and/or vaccine platforms.
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In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.
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Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.
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