Postdoctoral Fellow - Bioinformatics and Computational Biology - Dr. Maitituoheti
- Houston Methodist Academic Institute
- Location: Houston, TX
- Job Number: 7174178
- Posting Date: 3 months ago
- Application Deadline: Open Until Filled
Job Description
JOB SUMMARY
Computational postdoctoral fellow/associate position is available for a highly motivated candidate with a background in bioinformatics and a passion for exploring the epigenomic alterations in cancer progression and therapy resistance using the single cell and bulk high-throughput ChIP-Sequencing, ATAC-Seq, Hi-ChIP, etc. approaches.
A Ph.D. degree in an area of computational biology, bioinformatics, biostatistics, data science, or a related field is required. The candidate must have training in statistics and programming expertise, in particular R/Python and interest in the application of computational/statistical methods to complex datasets, relevant experience with single cell data analysis is a plus. The successful applicant will join a collaborative, interdisciplinary team and perform cutting-edge basic and/or translational research. The general research theme is to tackle biological problems with advanced computational and statistical methods. We highly value hard work, curiosity, innovation, teamwork, and professional development in combination with a healthy work/life balance.
The principal investigator of our laboratory is Dr. Maitituoheti. Projects will focus on the functional epigenomics with two directions towards: (1) understanding the role of epigenetic aberrations in early tumorigenesis, disease progression and the development of therapy resistance, and (2) searching for biomarkers and specific therapeutic targets for personalized cancer medicine.
PRIMARY JOB RESPONSIBILITIES
Job responsibilities labeled EF capture those duties that are essential functions of the job.
PEOPLE - 20%
Assists the physician in maintaining the functionality and operations of the Principal Investigator’s (PI) laboratory. (EF)
Promotes a positive work environment and leads the team to be dynamic and a focused work unit that actively helps one other to achieve optimal department results. Collaborates with all members of the department by actively communicating and reporting data in a comprehensive manner. (EF)
Role models to team members effective verbal, non-verbal and written communication, which includes active listening and teaching, assisting in development of such skills. (EF)
Provides contributions towards improvement of department scores for employee engagement, i.e. peer-to-peer accountability. (EF)
SERVICE - 20%
Develops research methods and performs research activities. (EF)
Documents research results and writes reports of results for presentation and/or publication in professional journals and other publications. (EF)
QUALITY/SAFETY - 20%
Follows all safety rules while on the job. Reports accidents promptly and corrects minor safety hazards. Communicates with peers and management regarding any hazards identified in the workplace. (EF)
Assists with implementation and education of department-based safety initiatives, standards of practice and protocols. Develops skills of team members and continually assists with improving skills, performance and outcomes. (EF)
Identifies opportunities for corrective action and process improvement providing recommendations and contributes to meeting department and laboratory targets for quality and safety. (EF)
FINANCE - 20%
Utilizes resources effectively and efficiently, demonstrating responsible financial stewardship. Manages own time effectively and prioritizes work to achieve maximum results in a timely manner. (EF)
Uses resources efficiently; does not waste supplies. Self-motivated to independently manage time effectively and prioritize daily tasks. (EF)
GROWTH/INNOVATION - 20%
Participates in pertinent research activities and evidenced-based practice projects. Participates in departmental projects and activities. Acts as a change agent. (EF)
Seeks opportunities to expand learning beyond baseline competencies with a focus on continual development. Remains current on professional issues and clinical skills. Completes and updates the My Development Plan on an on-going basis. Ensures own career discussions occur with appropriate management. (EF)
This job description is not intended to be all inclusive; the employee will also perform other reasonably related business/job duties as assigned. Houston Methodist reserves the right to revise job duties and responsibilities as the need arises.
EDUCATION REQUIREMENTS
o Postdoctoral Fellow 0, 1, 2, 3, 4 – Doctor of Medicine (MD) from an accredited medical school or Doctoral Degree (PhD) in medical field (A letter from the academic institution certifying that all student work is complete will be considered for Postdoctoral Fellow 0 only.)
EXPERIENCE REQUIREMENTS
o Postdoctoral Fellow 0– None
o Postdoctoral Fellow 1– One year of Postdoc experience
o Postdoctoral Fellow 2 – Two years’ Postdoc experience
o Postdoctoral Fellow 3 – Three years’ Postdoc experience
o Postdoctoral Fellow 4 – Four years’ Postdoc experience
License/Certification
CERTIFICATIONS, LICENSES AND REGISTRATIONS REQUIRED
o None
KNOWLEDGE, SKILLS AND ABILITIES REQUIRED
o Demonstrates the skills and competencies necessary to safely perform the assigned job, determined through on-going skills, competency assessments, and performance evaluations
o Sufficient proficiency in speaking, reading, and writing the English language necessary to perform the essential functions of this job, especially with regard to activities impacting patient or employee safety or security
o Ability to effectively communicate with patients, physicians, family members and co-workers in a manner consistent with a customer service focus and application of positive language principles
o Demonstrated knowledge of biomedical research
o Ability to work effectively in a fast-paced environment
o Demonstrates flexibility and adaptability in the workplace
SUPPLEMENTAL REQUIREMENTS
Work Attire Yes/No
Uniform No
Scrubs Yes
Business professional No
Other (dept approved) Yes
On-Call* No
*Note that employees may be required to be on-call during emergencies (ie. Disaster, Severe Weather Event, etc) regardless of selection above.
Travel**
May require travel within No
Houston Metropolitan area
May require travel outside No
of Houston Metropolitan area
**Travel specifications may vary by department.
Please note any other special considerations to this job: Work will be in a research laboratory environment.
Company Profile:
Houston Methodist Academic Institute was formed to rapidly and efficiently translate discoveries made in the laboratory and the clinic into new diagnostics, therapies and treatments. The Research Institute was created in 2004 to provide the infrastructure and support for these endeavors and to house the technology and resources needed to make innovative breakthroughs in important areas of human disease. A 540,000-square-foot building dedicated to research and clinical trials, the Academic Institute houses over 2,110 credentialed researchers conducting 1,387 ongoing clinical protocols.
Computational postdoctoral fellow/associate position is available for a highly motivated candidate with a background in bioinformatics and a passion for exploring the epigenomic alterations in cancer progression and therapy resistance using the single cell and bulk high-throughput ChIP-Sequencing, ATAC-Seq, Hi-ChIP, etc. approaches.
A Ph.D. degree in an area of computational biology, bioinformatics, biostatistics, data science, or a related field is required. The candidate must have training in statistics and programming expertise, in particular R/Python and interest in the application of computational/statistical methods to complex datasets, relevant experience with single cell data analysis is a plus. The successful applicant will join a collaborative, interdisciplinary team and perform cutting-edge basic and/or translational research. The general research theme is to tackle biological problems with advanced computational and statistical methods. We highly value hard work, curiosity, innovation, teamwork, and professional development in combination with a healthy work/life balance.
The principal investigator of our laboratory is Dr. Maitituoheti. Projects will focus on the functional epigenomics with two directions towards: (1) understanding the role of epigenetic aberrations in early tumorigenesis, disease progression and the development of therapy resistance, and (2) searching for biomarkers and specific therapeutic targets for personalized cancer medicine.
PRIMARY JOB RESPONSIBILITIES
Job responsibilities labeled EF capture those duties that are essential functions of the job.
PEOPLE - 20%
Assists the physician in maintaining the functionality and operations of the Principal Investigator’s (PI) laboratory. (EF)
Promotes a positive work environment and leads the team to be dynamic and a focused work unit that actively helps one other to achieve optimal department results. Collaborates with all members of the department by actively communicating and reporting data in a comprehensive manner. (EF)
Role models to team members effective verbal, non-verbal and written communication, which includes active listening and teaching, assisting in development of such skills. (EF)
Provides contributions towards improvement of department scores for employee engagement, i.e. peer-to-peer accountability. (EF)
SERVICE - 20%
Develops research methods and performs research activities. (EF)
Documents research results and writes reports of results for presentation and/or publication in professional journals and other publications. (EF)
QUALITY/SAFETY - 20%
Follows all safety rules while on the job. Reports accidents promptly and corrects minor safety hazards. Communicates with peers and management regarding any hazards identified in the workplace. (EF)
Assists with implementation and education of department-based safety initiatives, standards of practice and protocols. Develops skills of team members and continually assists with improving skills, performance and outcomes. (EF)
Identifies opportunities for corrective action and process improvement providing recommendations and contributes to meeting department and laboratory targets for quality and safety. (EF)
FINANCE - 20%
Utilizes resources effectively and efficiently, demonstrating responsible financial stewardship. Manages own time effectively and prioritizes work to achieve maximum results in a timely manner. (EF)
Uses resources efficiently; does not waste supplies. Self-motivated to independently manage time effectively and prioritize daily tasks. (EF)
GROWTH/INNOVATION - 20%
Participates in pertinent research activities and evidenced-based practice projects. Participates in departmental projects and activities. Acts as a change agent. (EF)
Seeks opportunities to expand learning beyond baseline competencies with a focus on continual development. Remains current on professional issues and clinical skills. Completes and updates the My Development Plan on an on-going basis. Ensures own career discussions occur with appropriate management. (EF)
This job description is not intended to be all inclusive; the employee will also perform other reasonably related business/job duties as assigned. Houston Methodist reserves the right to revise job duties and responsibilities as the need arises.
EDUCATION REQUIREMENTS
o Postdoctoral Fellow 0, 1, 2, 3, 4 – Doctor of Medicine (MD) from an accredited medical school or Doctoral Degree (PhD) in medical field (A letter from the academic institution certifying that all student work is complete will be considered for Postdoctoral Fellow 0 only.)
EXPERIENCE REQUIREMENTS
o Postdoctoral Fellow 0– None
o Postdoctoral Fellow 1– One year of Postdoc experience
o Postdoctoral Fellow 2 – Two years’ Postdoc experience
o Postdoctoral Fellow 3 – Three years’ Postdoc experience
o Postdoctoral Fellow 4 – Four years’ Postdoc experience
License/Certification
CERTIFICATIONS, LICENSES AND REGISTRATIONS REQUIRED
o None
KNOWLEDGE, SKILLS AND ABILITIES REQUIRED
o Demonstrates the skills and competencies necessary to safely perform the assigned job, determined through on-going skills, competency assessments, and performance evaluations
o Sufficient proficiency in speaking, reading, and writing the English language necessary to perform the essential functions of this job, especially with regard to activities impacting patient or employee safety or security
o Ability to effectively communicate with patients, physicians, family members and co-workers in a manner consistent with a customer service focus and application of positive language principles
o Demonstrated knowledge of biomedical research
o Ability to work effectively in a fast-paced environment
o Demonstrates flexibility and adaptability in the workplace
SUPPLEMENTAL REQUIREMENTS
Work Attire Yes/No
Uniform No
Scrubs Yes
Business professional No
Other (dept approved) Yes
On-Call* No
*Note that employees may be required to be on-call during emergencies (ie. Disaster, Severe Weather Event, etc) regardless of selection above.
Travel**
May require travel within No
Houston Metropolitan area
May require travel outside No
of Houston Metropolitan area
**Travel specifications may vary by department.
Please note any other special considerations to this job: Work will be in a research laboratory environment.
Company Profile:
Houston Methodist Academic Institute was formed to rapidly and efficiently translate discoveries made in the laboratory and the clinic into new diagnostics, therapies and treatments. The Research Institute was created in 2004 to provide the infrastructure and support for these endeavors and to house the technology and resources needed to make innovative breakthroughs in important areas of human disease. A 540,000-square-foot building dedicated to research and clinical trials, the Academic Institute houses over 2,110 credentialed researchers conducting 1,387 ongoing clinical protocols.
