Summary

The Department of Ophthalmology at Baylor College of Medicine seeks a qualified, highly motivated, and creative Postdoctoral Fellow to join the de Paiva’s lab. Dr. Cintia de Paiva's research focuses on understanding of the interplay of aging and cathepsin S and the generation of autoreactive T cells on the ocular surface and lacrimal gland. The Postdoctoral Fellow will work closely with the PI and other lab personnel performing complex research and research techniques. Duties may include but are not limited to designing and conducting experiments in a controlled laboratory setting. Duties may include performing experiments, collecting, analyzing, and reporting data; designing immunohistochemistry with proper controls and proper detection of colorimetric reactions, (HRP, alkaline phosphatase, streptavidin, etc.); designing and performing flow cytometry with fluorescence minus controls, positive and negative controls in cervical lymph nodes, collagenase-digested lacrimal glands, and spleens; designs and perform intracellular staining for interferon-gamma, IL-17, and TNF; analyze data using FlowJo software; work with animals, including genotyping, husbandry and inducing dry eye protocol; administer oral gavage, ocular topical eye drops, and subconjunctival injections as needed; design and perform real-time PCR Taqman Probes; analyze data using the delta-delta CT method. The Postdoctoral Associate is responsible for maintaining oversight and ensuring that laboratory equipment and supplies are clean and sterile and maintains the cleanliness of the laboratory, and orders laboratory supplies and equipment. 

Candidates must have good communication skills and be willing to work with other lab members as a team. Expertise in the application and adaptation of numerous research techniques and procedures is also required.

The Department of Ophthalmology and the Cullen Eye Institute provide educational programs for ophthalmology residents and fellows, medical and graduate students, research scientists, and practicing ophthalmologists; support research in the structure, function, and diseases of the eye and the visual system; offer the highest quality eye care available, and sponsor public programs for the prevention of eye disease and injury.  Physicians at the Alkek Eye Center and at Baylor Vision are improving patients' vision and advancing the treatment of eye diseases and disorders.  We offer exceptional clinical and surgical care, innovative, advanced treatment options based on the latest research, and state-of-the-art facilities and equipment. We invite you to learn more about our nationally and internationally recognized physicians and our cutting-edge translational research.

Job Duties

• Plans, directs, and conducts specialized and advanced research experiments.
• Evaluates and analyzes data.
• Establishes new research protocols and procedures.
• Summarizes research findings and publishes results in research journals.
• Maintains laboratory operations.
• Supervises research staff.

Minimum Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

Preferred Qualifications

• Previous experience in cellular or molecular biology or immunology research, either as a Ph.D. candidate or post-doctoral fellow.
• Proficiency with experimental design and analysis.
• Proficiency in performing basic molecular techniques such as tissue dissection, cell isolation and sorting, and immunostaining.
• Ability and willingness to work independently while part of a dynamic research team.
• English writing skills.
• Authorization to work in the U.S.
• Experience with rodent care and animal husbandry or willingness to be trained in animal handling and husbandry techniques is acceptable.
• Experience with basic cell and molecular biology techniques.