Postdoctoral Research Associate
- Brown University
- Location: Providence, RI
- Job Number: 7160298
- Posting Date: Jul 26, 2023
- Application Deadline: Oct 31, 2023
Job Description
Position Description:
The Department of Molecular Biology, Cell Biology & Biochemistry at Brown University is seeking a Postdoctoral Associate to join the laboratory of Dr. Hongwei Yao, Associate Professor (Research). Dr. Yao’s laboratory focuses on metabolic reprogramming and senescence during normal lung development, the development of bronchopulmonary dysplasia and associated pulmonary hypertension using human peripheral tissues, small and larger animal models, and cell culture. The laboratory pursues multidisciplinary approaches, including metabolomics, metabolic flux assay, single cell RNA sequencing, genetic lineage tracing, as well as traditional molecular and physiopathological methods.
The duty of the postdoctoral associate is to study metabolic mechanisms in the pathogenesis of bronchopulmonary dysplasia and associated pulmonary hypertension, as well as to identify therapeutic targets for these diseases using in vitro cell culture, animal models and human peripheral tissues. The postdoctoral associate will perform hyperoxic exposure, drug administration, and nanoparticle-mediated gene delivery. In addition, the candidate is experienced in Western blot, immunoprecipitation, qRT-PCR, immunohistochemistry, immunofluorescence, and biochemical analysis. She or he is willing to learn new techniques, including lineage tracing experiments, single cell RNA sequencing and spatial transcriptomics. The postdoctoral associate will also assist in the technical training and supervision of technicians and students. The postdoctoral associate will participate actively in relevant seminars, journal clubs and conferences. The applicant will be responsible for generating and preparing the data that will go in reports and presentations as well as for manuscript publications. Finally, the postdoctoral associate will also assist in planning/drafting relevant portions of extramural grants to continue support of the project.
Salary is commensurate with experience, per Brown's postdoctoral salary scale (which matches the NIH Postdoctoral Stipend scale).
Qualifications:
Applicants must have completed all requirements for a doctoral degree before start of the position or have completed no more than one prior postdoctoral fellowship. Candidates are expected to have intensive experiences in small animal procedures, cell culture, and/or molecular biology. Candidates with solid background in metabolism, aging/senescence, and/or lung biology are particularly encouraged to apply. Strong time management, communication and writing skills, and the ability to work both independently and as a part of a team are required.
Application Instructions:
Applicants should submit a CV, statements of teaching philosophy and research interests, up to three representative publications, and names of three references to Interfolio (linked).
Application review will begin August 15, 2023.
As an EEO/AA employer, Brown University provides equal opportunity and prohibits discrimination, harassment and retaliation based upon a person’s race, color, religion, sex, age, national or ethnic origin, disability, veteran status, sexual orientation, gender identity, gender expression, or any other characteristic protected under applicable law, and caste, which is protected by our University policies.
The MCB Department at Brown is committed to centering efforts to diversity, equity and inclusion in all our activities, and to constituting a community that welcomes members regardless of identity. The statement of MCB department Diversity & Inclusion Action Plan includes the commitment to diversity and inclusion on topics of People, Academic Excellence, Curriculum, Community, Knowledge, and Accountability.
The Department of Molecular Biology, Cell Biology & Biochemistry at Brown University is seeking a Postdoctoral Associate to join the laboratory of Dr. Hongwei Yao, Associate Professor (Research). Dr. Yao’s laboratory focuses on metabolic reprogramming and senescence during normal lung development, the development of bronchopulmonary dysplasia and associated pulmonary hypertension using human peripheral tissues, small and larger animal models, and cell culture. The laboratory pursues multidisciplinary approaches, including metabolomics, metabolic flux assay, single cell RNA sequencing, genetic lineage tracing, as well as traditional molecular and physiopathological methods.
The duty of the postdoctoral associate is to study metabolic mechanisms in the pathogenesis of bronchopulmonary dysplasia and associated pulmonary hypertension, as well as to identify therapeutic targets for these diseases using in vitro cell culture, animal models and human peripheral tissues. The postdoctoral associate will perform hyperoxic exposure, drug administration, and nanoparticle-mediated gene delivery. In addition, the candidate is experienced in Western blot, immunoprecipitation, qRT-PCR, immunohistochemistry, immunofluorescence, and biochemical analysis. She or he is willing to learn new techniques, including lineage tracing experiments, single cell RNA sequencing and spatial transcriptomics. The postdoctoral associate will also assist in the technical training and supervision of technicians and students. The postdoctoral associate will participate actively in relevant seminars, journal clubs and conferences. The applicant will be responsible for generating and preparing the data that will go in reports and presentations as well as for manuscript publications. Finally, the postdoctoral associate will also assist in planning/drafting relevant portions of extramural grants to continue support of the project.
Salary is commensurate with experience, per Brown's postdoctoral salary scale (which matches the NIH Postdoctoral Stipend scale).
Qualifications:
Applicants must have completed all requirements for a doctoral degree before start of the position or have completed no more than one prior postdoctoral fellowship. Candidates are expected to have intensive experiences in small animal procedures, cell culture, and/or molecular biology. Candidates with solid background in metabolism, aging/senescence, and/or lung biology are particularly encouraged to apply. Strong time management, communication and writing skills, and the ability to work both independently and as a part of a team are required.
Application Instructions:
Applicants should submit a CV, statements of teaching philosophy and research interests, up to three representative publications, and names of three references to Interfolio (linked).
Application review will begin August 15, 2023.
As an EEO/AA employer, Brown University provides equal opportunity and prohibits discrimination, harassment and retaliation based upon a person’s race, color, religion, sex, age, national or ethnic origin, disability, veteran status, sexual orientation, gender identity, gender expression, or any other characteristic protected under applicable law, and caste, which is protected by our University policies.
The MCB Department at Brown is committed to centering efforts to diversity, equity and inclusion in all our activities, and to constituting a community that welcomes members regardless of identity. The statement of MCB department Diversity & Inclusion Action Plan includes the commitment to diversity and inclusion on topics of People, Academic Excellence, Curriculum, Community, Knowledge, and Accountability.
