Postdoctoral Fellow
- University of North Carolina at Chapel Hill
- Location: Chapel Hill, NC
- Job Number: 7143556
- Posting Date: May 3, 2023
- Salary / Pay Rate: NIH Scale
- Application Deadline: Open Until Filled
Job Description
The Rau Lab (www.raulab.web.unc.edu) in the Computational Medicine Program at The University of North Carolina at Chapel Hill is searching for a collaborative, eager Postdoctoral Fellow to study the role of multinucleated cardiomyocytes in heart failure using a spatial transcriptomics approach
Our team is broadly interested in the genetic basis of heart failure, with a hybrid dry/wet approach that blends classic and cutting-edge bench science techniques with new computational approaches. We utilize large panels of inbred mice to perform systems-level analyses. We have recently received funding to explore whether multinucleated cardiomyocytes are expressing distinct transcriptional profiles at each nucleus within a multinucleated cell. We are looking to hire a postdoctoral fellow interested in exploring this question through the lens of sub-cellular-resolution spatial transcriptomics (eg smFISH, merFISH, seqFISH) and who will drive research forward into independent lines of inquiry, mentor undergraduate and graduate students, and interact with other members of the cardiovascular and systems genetics fields.
We Value:
• Curiosity: A desire to understand how the body works and discover new things.
• Collaboration: By working with others, be they in the lab, down the hall, or somewhere else in the world, we improve all of our research.
• Drive: We work in an exciting, quick-moving field. We look for colleagues who are interested in pursuing exciting, novel projects and seeing them through to completion
• Balance: We know that to do our best work, we need to have sufficient time each week to recharge, and plan our schedules accordingly.
This position requires a Doctorate Degree (PhD) in Molecular Biology, Genetics, Biology or related field at the time of appointment. Highly motivated candidates interested in studying the genetics of cardiac physiology are encouraged to apply.
Successful applicants will:
• Have significant wet lab experience, ideally working with mice and immunofluorescence microscopy
• Have an interest in interacting with and collaborating with bioinformaticians before, during, and after experiments
• Have exposure to R and/or a willingness to learn
• Have exposure to genomic concepts and technologies such as GWAS, Next Generation Sequencing, Single Cell techniques, etc.
• Be collaborative, creative, and a team player
The Computational Medicine Program at UNC is a team of PIs and researchers dedicated to utilizing the power of computational techniques and bench science approaches to improve human health. UNC is located in the NC Research Triangle, a hub for biomedical research and industry, with significant opportunities for collaboration and career development. Chapel Hill is a vibrant small town surrounded by trees with great hiking trails and an excellent quality of life.
To apply: Interested applicants should submit their curriculum vitae, a summary (2 pages max) of their research interests and experience, and contact information for three references to Dr. Christoph Rau ([email protected]). Please also apply to the posting at https://unc.peopleadmin.com/postings/255351 Review of applications will begin immediately and continue until the position is filled. We are hoping to find someone interested in joining the lab over this summer.
Our team is broadly interested in the genetic basis of heart failure, with a hybrid dry/wet approach that blends classic and cutting-edge bench science techniques with new computational approaches. We utilize large panels of inbred mice to perform systems-level analyses. We have recently received funding to explore whether multinucleated cardiomyocytes are expressing distinct transcriptional profiles at each nucleus within a multinucleated cell. We are looking to hire a postdoctoral fellow interested in exploring this question through the lens of sub-cellular-resolution spatial transcriptomics (eg smFISH, merFISH, seqFISH) and who will drive research forward into independent lines of inquiry, mentor undergraduate and graduate students, and interact with other members of the cardiovascular and systems genetics fields.
We Value:
• Curiosity: A desire to understand how the body works and discover new things.
• Collaboration: By working with others, be they in the lab, down the hall, or somewhere else in the world, we improve all of our research.
• Drive: We work in an exciting, quick-moving field. We look for colleagues who are interested in pursuing exciting, novel projects and seeing them through to completion
• Balance: We know that to do our best work, we need to have sufficient time each week to recharge, and plan our schedules accordingly.
This position requires a Doctorate Degree (PhD) in Molecular Biology, Genetics, Biology or related field at the time of appointment. Highly motivated candidates interested in studying the genetics of cardiac physiology are encouraged to apply.
Successful applicants will:
• Have significant wet lab experience, ideally working with mice and immunofluorescence microscopy
• Have an interest in interacting with and collaborating with bioinformaticians before, during, and after experiments
• Have exposure to R and/or a willingness to learn
• Have exposure to genomic concepts and technologies such as GWAS, Next Generation Sequencing, Single Cell techniques, etc.
• Be collaborative, creative, and a team player
The Computational Medicine Program at UNC is a team of PIs and researchers dedicated to utilizing the power of computational techniques and bench science approaches to improve human health. UNC is located in the NC Research Triangle, a hub for biomedical research and industry, with significant opportunities for collaboration and career development. Chapel Hill is a vibrant small town surrounded by trees with great hiking trails and an excellent quality of life.
To apply: Interested applicants should submit their curriculum vitae, a summary (2 pages max) of their research interests and experience, and contact information for three references to Dr. Christoph Rau ([email protected]). Please also apply to the posting at https://unc.peopleadmin.com/postings/255351 Review of applications will begin immediately and continue until the position is filled. We are hoping to find someone interested in joining the lab over this summer.
