Are you an ambitious researcher looking for your next challenge? Are you interested in applying your research skills to develop new methods to improve resolution for healthcare applications?

You will join an EPSRC Open Fellowship project in the group of George Heath which aims to develop new Atomic Force Microscopy methods to improve spatial resolution and quantitatively map interactions with microsecond and at sub-nanometre resolution.

To better understand the behaviour of any disease and to develop treatment options for it, we need to understand processes occurring on the single molecule level as well as the cellular and tissue levels. However, biomolecules are highly dynamic and have complex structures which are difficult to observe simultaneously. Biomolecules such as DNA and proteins interact with many other molecules to perform their biological function. Exploiting these interactions with molecules such as drugs, to block or enhance function can be used to treat or prevent diseases. However, few experimental techniques can capture this information at the relevant spatiotemporal scales. In this project you will work experimentally develop AFM methods to enable near atomic resolution imaging of single biomolecules interacting with binding partners.

With a PhD (or have submitted your thesis prior to taking up the appointment) in Physics, Chemistry, Biophysics or a related field, you will have experience in atomic force microscopy of biological samples and a developing track record of peer reviewed publications in international journals.

What we offer in return

And much more!  

To explore the post further or for any queries you may have, please contact: 

Dr. George Heath, University Academic Fellow

Tel: +44 (0)113 343 9718 or email: [email protected]