Computational postdoctoral associate position is available for a highly motivated candidate with a background in bioinformatics and a passion for exploring the epigenomic alterations in cancer progression and therapy resistance using the single cell and bulk high-throughput ChIP-Sequencing, ATAC-Seq, Hi-ChIP, etc. approaches. Projects will focus on the biology and epigenomics of breast and ovarian cancers, the identification of novel epigenetic therapeutic strategies and targets, and the mechanisms underlying targeted and immuno-therapy resistance.
A Ph.D. degree in an area of computational biology, bioinformatics, biostatistics, data science, or a related field is required. The candidate must have training in statistics and programming expertise, in particular R/Python and interest in the application of computational/statistical methods to complex datasets, relevant experience with single cell data analysis is a plus. The successful applicant will join a collaborative, interdisciplinary team and perform cutting-edge basic and/or translational research. The general research theme is to tackle biological problems with advanced computational and statistical methods. We highly value hard work, curiosity, innovation, teamwork, and professional development in combination with a healthy work/life balance.

The principal investigator of our laboratory is Dr. Mayinuer Maitituoheti, an assistant professor in the Department of Surgery, Immunobiology and Transplant Science Center. Dr. Maitituoheti received her Ph.D. degree from Huazhong University of Science & Technology and postdoctoral training in the laboratory of Dr. Kunal Rai at the MD Anderson Cancer Center. Dr. Maitituoheti has identified many functional epigenetic elements associated with cancer development and immunotherapy resistance. Dr. Maitituoheti has an outstanding publication record (Nature communications 2022, Cell Reports 2021, Cell Reports 2020, Cancer Cell 2020), please find a complete list of her publications by clicking here. Our laboratory is interested in the functional epigenomics of breast and ovarian cancers with two preliminary directions towards: (1) understanding the role of epigenetic aberrations in early tumorigenesis, disease progression and the development of therapy resistance, and (2) searching for biomarkers and specific therapeutic targets for personalized cancer medicine.
Please send a curriculum vitae, a cover letter stating research interests and career goals, and names and contact information of three references to: [email protected].

Houston Methodist is an academic medical center that is affiliated with Weill Cornell Medical College and the Weill Cornell Graduate School of Medical Sciences of Cornell University. Houston Methodist offers NIH standard postdoc salary and excellent benefits in a smoke and drug-free workplace. Houston Methodist is an equal opportunity employer and encourages applications from under-represented groups.