Post-doctoral Fellow in Cancer Biology and Drug Discovery
- Oregon State University
- Location: Portland, OR
- Job Number: 7107630
- Posting Date: Aug 9, 2022
- Application Deadline: Open Until Filled
Job DescriptionA Post-doctoral position is immediately available to join the Indra laboratory in a collaborative Department of Defense (DOD) funded Team Science project between UAB and OSU to investigate the role of CYP11A1 derived novel vitamin D metabolites in prevention of UVB induced melanoma. In collaboration, we discovered a new pathway of vitamin D metabolism and generated a new mouse model lacking VDR in different skin cells. We now seek to determine the function of novel metabolites in genetic and epigenetic control of prevention of melanoma promotion and progression, control of cancer-cell metabolism and immune-activation through ligand-receptor interactions.
Additional Application Information:
We are looking for a self-driven and highly motivated candidate, MD or PhD (within 1-2 years after PhD), possess a strong ability to lead a collaborative research project, with capabilities to work both independently and as a team. The candidate is expected to have strong work ethics, great interpersonal skills and excellent oral and written communication skills.
We have a track record of training the best and the brightest graduate and post-doctoral candidates who have all landed in independent positions in academia or in industry. We strive for work/life balance and put forward trainee growth and success in life as the highest priority.
1. Experience in Cell culture, cloning, transfections/transductions, gene editing and other cell based assays.
2. Expertise in molecular techniques such as western blot, IP/co-IP, IHC and ICC, northern blot, RT-qPCR, ChIP and PLA assay.
3. Experience with small laboratory animals (e.g. mice or rats), including colony maintenance, blood collections, IV or s.c. injections and necropsy.
4. Excellent skills to manage data/results and maintain lab notebook (hard copy and electronic version).
5. Experience in handling computer software e.g. Microsoft office, Adobe Creative Suite, EndNote, BioRender etc.
1. Background in immunology, skin and cancer biology, cell signaling, epigenetics.
2. Experience with multi-omics approach (transcriptomics, proteomics, metabolomics).
3. Skills in Bioinformatics and statistics (e.g. ImageJ, R, Python, GraphPad Prism).
4. Experience in high throughput screen of bioactive natural products and small molecules.
5. Skills in Flow cytometry including sorting and multiparameter FACS analysis.
6. Promotes and supports diversity, equity and inclusivity.
7. Lab management and maintenance, which includes ordering, receiving, properly storing reagents and updating lab inventory.
8. Designing and performing experiments independently with a limited supervision.
9. Data analyses and reporting in scientific meetings, writing manuscripts.
10. Mentoring graduate and undergraduate trainees in the lab.
The successful candidate will work in a multi-cultural, all-inclusive, highly interactive research environment in the Department of Pharmaceutical Sciences, OSU-OHSU College of Pharmacy in Corvallis, Oregon, USA.
Corvallis is a beautiful and safe college town close to Portland, Oregon, with close proximity to pacific ocean and scenic beaches on one side and mountains and famous ski-resorts on another side. It offers unique cultural attractions, low cost of living and a high quality of life. There is funding for 3 years, renewable each year based on academic performance and success.
Interested candidates should contact Dr. Arup K. Indra [email protected] and refer to "postdoc application"
To apply: Please send a single PDF with a cover letter summarizing your research training and accomplishments, a personal statement of scientific interests and goals, your CV/resume with complete list of publications and names with contact emails/addresses of three referees.
OSU values a diverse and culturally competent workforce and commits to an inclusive excellence by advancing equity and diversity in all that we do. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation, contact the Affirmative Action and Equal Opportunity Access (EOA) at 541-737-3556 or [email protected]
Application Deadline: Applications will be accepted until suitable candidate is identified.