- University of Leeds
- Location: Leeds, United Kingdom
- Job Number: 7106349 (Ref #: MHLMR1091)
- Posting Date: Jul 26, 2022
Do you have a background in cancer biology, cancer immunotherapy or virology? Do you want to further your research career in one of the UK’s leading research-intensive Universities?
Assessment of oncolytic virus therapy using patient-derived Ewing Sarcoma models
We are seeking a post-doctoral research fellow to work on a project investigating virus-based treatments of Ewing Sarcoma. This is a joint project between the labs of Dr Fiona Errington-Mais, Professor Sue Burchill and Professor Graham Cook in the School of Medicine. This project will use patient-derived Ewing Sarcoma cell cultures and a range of cell biology, immunological and computational methods to explore the therapeutic potential of oncolytic viruses against Ewing Sarcoma.
Cancer-killing, or “oncolytic” viruses are increasingly used to evoke therapeutic responses in cancer patients because of their multi-modal mechanism of action. Oncolytic viruses can directly kill cancer cells by preferentially replicating in cancer cells (not normal cells) and can activate our immune system to kill cancer cells, thereby acting as a cancer immunotherapy. Cancer immunotherapies are showing increasing promise for the treatment of otherwise incurable malignancies. This project, which is funded by Sarcoma UK, will identify oncolytic viruses that directly kill Ewing Sarcoma cells, explore biomarkers of response, and establish the potential role for oncolytic virus activated natural killer (NK) cells for therapy.
The successful candidate will have a background in biomedical research, specifically in cancer biology, immunology, and/or virology and be interested in applying your expertise to Ewing Sarcoma. You will join a team of researchers focussing on oncolytic virus-based cancer research, cancer immunology and Sarcoma cell biology.
To explore the post further or for any queries you may have, please contact:
Dr Fiona Errington-Mais - Email: [email protected]
Professor Sue Burchill - Email: [email protected]
Professor Graham Cook - Email: [email protected]
As an international research-intensive university, we welcome students and staff from all walks of life and from across the world. We foster an inclusive environment where all can flourish and prosper, and we are proud of our strong commitment to student education. Within the Faculty of Medicine & Health we are dedicated to diversifying our community and we welcome the unique contributions that individuals can bring, and particularly encourage applications from, but not limited to Black, Asian, people who belong to a minority ethnic community, people who identify as LGBT+; and people with disabilities. Candidates will always be selected based on merit and ability.
|Location:||Leeds - St James University Hospital|
|Faculty/Service:||Faculty of Medicine & Health|
|School/Institute:||Leeds Institute of Medical Research (LIMR)|
|Section:||Haematology & Immunology|
|Salary:||£34,304 to £40,927 p.a.|
|Working Time:||Full-time 1.0fte|
|Post Type:||Full Time|
|Contract Type:||Fixed Term (Available from 1 October 2022 for two years due to external grant income)|
|Release Date:||Monday 25 July 2022|
|Closing Date:||Tuesday 30 August 2022|
The University community is made up of a wide range of people with diverse backgrounds and circumstances, which we value and regard as a great asset. As part of our continued commitment to equality and inclusion, we strive to create an environment where everyone can reach their full potential and have a real opportunity to participate in and contribute to our activities.