A postdoctoral fellowship is currently available in the Department of Radiology
and Biomedical Imaging at the University of California, San Francisco (UCSF)
working with Drs. Engel, Wilson and Ohliger to study the metabolic imaging of
infection using bacteria-specific PET, hyperpolarized 13C MRI, and deuterium
spectroscopy methods. Both D-amino acid and para-aminobenzoic acid (PABA)-
derived radiotracers and hyperpolarized 13C spectroscopy methods have been
reported:
https://pubs.acs.org/doi/10.1021/acscentsci.9b00743;
https://pubs.acs.org/doi/abs/10.1021/acsinfecdis.9b00196;
https://pubs.acs.org/doi/10.1021/acsinfecdis.7b00234;
https://pubs.acs.org/doi/full/10.1021/acsinfecdis.8b00061;
https://pubmed.ncbi.nlm.nih.gov/33637588/
The ideal candidate will have a strong background in biochemistry, microbiology,
structural biology and the use of preclinical animal models. The most relevant
experience would be with in vitro and in vivo models of biofilm development.
The successful applicant will work as part of a collaborative team and have
access to a wide range of equipment, including at μPET/CT scanner, on-site
cyclotron, 18F and 11C synthesis modules, hot cells, and liquid scintillation
equipment. A dedicated cell and molecular biology laboratory, fully equipped for
biological assays as well as a recently installed state of the art LC-MS system
are used for complementary investigations.
If interested please contact Drs. David Wilson or Joanne Engel:
[email protected]; [email protected]