A postdoctoral fellowship is currently available in the Department of Radiology
and Biomedical Imaging at the University of California, San Francisco (UCSF)
working with Drs. Wilson, Ohliger, Chaumeil, Sriram and Gordon to study the
metabolic imaging of infection using hyperpolarized 13C MRI and 2H methods.
We have pursued positron emission tomography (PET), hyperpolarized 13C
spectroscopy, and 2H methods in this area as well as developed new tools for
modulation of bacterial genes:
https://pubs.acs.org/doi/10.1021/acscentsci.9b00743;
https://pubs.acs.org/doi/abs/10.1021/acsinfecdis.9b00196;
https://pubs.acs.org/doi/10.1021/acsinfecdis.7b00234;
https://pubs.acs.org/doi/abs/10.1021/acs infecdis.8b00061;
https://pubmed.ncbi.nlm.nih.gov/30617347/.
The ideal candidate will have a strong background in MR spectroscopy,
biochemistry, metabolism, and the use of preclinical animal models. A relevant
experience would be previous work with bacteria.
The successful applicant will work as part of a collaborative team and have
access to a wide range of equipment, including several dynamic nuclear
polarization (DNP) polarizers, and several platforms for NMR/ small animal MRS.
A dedicated cell and molecular biology laboratory, fully equipped for biological
assays as well as a recently installed state of the art LC-MS system are used for
complementary investigations.
If interested please contact Dr. David Wilson: [email protected].