About City of Hope

City of Hope is an independent biomedical research and treatment organization for cancer, diabetes, and other life-threatening diseases.

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution.  AccessHope™, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hope’s specialized cancer expertise.

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

City of Hope’s commitment to Diversity, Equity, and Inclusion

We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all our communities.  Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds, and experiences to our work -- and that our teams align with the people we serve to build trust and understanding.  We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds, and perspectives; this is reflected in our work and represented in our people.

Position Summary

Dr. John Shively laboratory specializes in studying the CEA gene family. More specifically, he researches the use of anti-CEA antibodies for tumor imaging and therapy, as well as the role of CEACAM1 in T-cell activation and mammary epithelial cell polarization. Currently research projects are focused on antibody and T cell-based immunotherapy in colon and breast cancer models. Furthermore, the preclinical studies investigate combination of radiotherapy with immunotherapy both against primary and metastatic tumors. Lab is also developing new anti-tumor immunocytokines and bispecific antibodies that are being tested in vitro and in vivo.

Basic education, experience and skills required for consideration:

• A Ph.D. degree in life or biomedical sciences, or a related discipline is required.
• Ability to work independently, to plan, manage and execute research projects
• Candidates must have demonstrated research ability (minimum of three first-author publications in peer-reviewed English journals) and strong communication skills (both speaking and writing)
• Expertise in molecular biology and immunology technics like cell culture, immunofluorescence, immunohistochemistry, western blotting, flow cytometry, live-cell imaging
• Proficient with computers specifically MS Office (which includes, Excel, Access, Word and PowerPoint) and statistical analysis software

Additional Information:

As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer.  All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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