Post-doctorate Research Fellowship at intersection of endocrinology, vascular and bone biology
- JOHNS HOPKINS UNIVERSITY
- Location: Baltimore, MD
- Job Number: 7092203
- Posting Date: Jan 13, 2022
- Application Deadline: Open Until Filled
Post-doctoral position at The Johns Hopkins University School of Medicine in the laboratory of Dr. Janet Crane
A post-doctoral position is available in the laboratory of Dr. Janet Crane, Department of Pediatrics/Division of Endocrinology and Department of Orthopedic Surgery/Center for Musculoskeletal Research (CMR). Dr. Crane’s focus is on skeletal fragility/bone health in children, particularly on glucocorticoid-induced osteoporosis in children. Dr. Crane has found the high-dose glucocorticoids decrease in skeletal angiogenesis precedes the decrease in bone volume and is focusing studies now on understanding the cellular mechanism and translational implications. Dr. Crane was recently awarded an R01 through the NIH/NAIMS to study the role of glucocorticoid-suppression of preosteoclast PDGF-BB in skeletal angiogenesis. The project uses novel mouse models and biomechanical and histological analyses. A prior funded project complements the basic science study with a clinical registry and biorepository of patients with Duchenne muscular dystrophy on chronic steroids with endocrine complications that can be utilized for further translational studies. The ultimate goal is identify biomarkers for the diagnosis of osteoporosis before sustaining a fracture and for monitoring efficacy of treatment response in children on chronic steroids.
EDUCATION AND EXPERIENCE REQUIRED
The applicants must have a PhD, MD or MD/PhD degree. We seek a highly motivated scientist who can work independently with strong written and oral English communication skills. The project involves the use of genetically engineered mice, molecular biology techniques, including endocrinology, bone and vascular biology. Prior experience in musculoskeletal, vascular, or endocrine-related fields is valued.
Full-time position with a young, dynamic team for 2-4 years. Opportunity to collaborate with additional projects and faculty within the CMR. Excellent training and mentorship to help launch an independent research career.
To apply for this position, please email a cover letter addressing past research experience and career goals and C.V. to: Dr. Janet Crane at [email protected]
The position is available immediately. Applications will be considered until the position is filled.