About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research.  City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation’s leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary:

The Beckman Research Institute of City of Hope is looking for highly motivated and creative Postdoctoral Fellows to work in either of the following areas within the laboratories of Dr. Ling Li, Associate Professor in the Department of Hematological Malignancies Translational Science, and Gehr Family Center for Leukemia Research:

1) Identification of novel anti-leukemia target using high-throughput CRISPR genetic screen (e.g., metabolic pathway)

2) Understanding the role of essential post-translational modification during leukemogenesis and development of novel inhibitor to reverse the malignant transformation

3) Genomic analysis of myeloid cancers development using high-throughput single-cell technology

The group conducts the most forefront science and is highly productive with publications in high-impact journals such as Cell Stem Cell, Blood, Haematologica, etc. in the past two years. Dr. Li's research program is supported by several NIH (R01 NHLBI, R01 NCI) and American Cancer Society awards. City of Hope is in the pleasant city of Los Angeles of Southern California.

Key Responsibilities:

• Devise, plan, document and advance basic science and translational projects in the relevant research area
• Collect data for grant applications and prepare manuscripts for publication
• Work in close collaboration with other team members and external partners from academia and industry, including presentation of progress internally or externally
• Train and supervise technical staff

Basic education, experience and skills required for consideration:

• A Ph.D. degree with a strong background and profound knowledge in the field of either molecular biology, immunology, cancer biology, or genetics
• Experience in sequencing or protein structural data analysis is highly preferred
• Previous experience in working with animal models of human cancers
• Literature knowledge of the research areas mentioned above
• Evidence of scientific rigor and excellence as documented by peer-reviewed publications
• Strong team player with excellent communication skills and fluency in English, both spoken and written
• Commitment to the program for three years

Additional Information:

• For more information on Dr. Ling Li’s research please visit here
• To protect the health of patients and staff and to comply with new State of California mandates, City of Hope staff are required to show proof of full vaccination by September 30, 2021.  Compliance is a condition of employment.   

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer.  All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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