Postdoctoral Fellow, Section of the Translational Breast Cancer Research, Breast Medical Oncology
- The University of Texas M. D. Anderson Cancer Center
- Location: Houston, TX
- Job Number: 7079710
- Posting Date: Jun 10, 2021
- Application Deadline: Open Until Filled
Job DescriptionJob Description
We seek highly motivated post-doctoral research fellows to investigate the development of new therapeutic approaches for the breast cancer. Prior experience in molecular and cell biology, as well as immunology is highly desirable. The candidate must be self-driven, ethical, and a team player.
Function: Carrying out studies of early drug development and tumor immune microenvironment in breast cancer.
Scope: 1) evaluation of anti-cancer drugs and elucidate the mechanism of action of drugs, 2) investigating tumor immune microenvironment and immune-regulatory pathways in breast cancer.
Essential job functions:
1. Extracts genomic DNA, RNA, or proteins for purposes of further downstream analysis.
2. Cell sorting and flow cytometry using cell lines and tumor tissues.
3. Prepares and conducts in vivo studies.
4. Prepares and conducts ex vivo/in situ histologic analyses using the following techniques: animal dissection, tissue fixation, paraffin embedding, cryofixation, immunohistochemistry, and immunofluorescence staining.
5. Analyze data, prepare graphs, figures, and help in writing and submitting the manuscript.
6. Reads literature relevant to cancer biology, inflammation, tumor microenvironment.
7. The postdoc must communicate freely and clearly, and must confer with superiors regarding new procedures and modify them according to the needs of the project.
8. Records and evaluates data obtained in accordance with methods requested and confers with superiors regarding results obtained.
9. Constructs, assembles and operates laboratory apparatus and equipment including thermocyclers, agarose gel electrophoresis units, nebulizers/gas compressors, and spectrophotometers.
1. Presents Journal Club or own project data in formal laboratory meetings
2. Present data in national and international meetings in form of posters or podium talks.
Experience: required basic molecular biology, immunology techniques, and mouse xenograft models.
The laboratory environment may involve occasional exposure to hazardous equipment and materials. The position will require animal handling (mice), as well as occasional handling of hazardous materials (small molecules, bacteria, and lentivirus) with proper personal protective equipment. Usage and safety training will be given.
PI: Naoto T. Ueno, MD, PhD
Research profile: https://mdanderson.elsevierpure.com/en/persons/naoto-t-ueno
Please apply for the position via the following link.
Breast Medical Oncology, Req #: 600143-00002
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html