About City of Hope

City of Hope is an independent biomedical research and treatment organization for cancer, diabetes and other life-threatening diseases.

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution.  AccessHope™, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hope’s specialized cancer expertise.

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

City of Hope’s commitment to Diversity, Equity and Inclusion

We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all of our communities.  Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds and experiences to our work -- and that our teams align with the people we serve in order to build trust and understanding.  We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds and perspectives; this is reflected in our work and represented in our people.

Position Summary

We are looking for a highly motivated and productive postdoctoral fellow for stem cell research projects within the Department of Developmental and Stem Cell Biology (Shi laboratory) at Beckman Research Institute of City of Hope.

Key Responsibilities include:

• This fellow will work on human induced pluripotent stem cell (iPSC)-based disease modeling and therapeutic development, including human iPSC derivation, CRISPR/Cas9-mediated gene editing, neural differentiation of human iPSCs, cell transplantation into relevant mouse models, and characterizing transplanted mice using biochemical, immunohistochemistry, and behavioral tests.
• This fellow is expected to write progress reports, high quality manuscripts for publication, postdoctoral fellowship applications, and help to generate data and ideas for grant applications.

Basic education, experience and skills required for consideration:

• A Ph.D. or MD degree in biomedical research, or a related discipline is required.
• Experience in human iPSC derivation and neural differentiation, gene editing, and excellent writing and verbal communication skills.

Additional Information:

As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.

• For more information about Dr. Yanhong Shi's research, please click here.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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