Postdoctoral Fellow - Diabetes Complications and Metabolism
- City of Hope
- Location: Duarte, CA
- Job Number: 7079620 (Ref #: 10011479)
- Posting Date: Apr 12, 2022
- Application Deadline: Open Until Filled
City of Hope, an innovative biomedical research,treatment and educational institution with over 6,000 employees, is dedicatedto the prevention and cure of cancer, type 1 diabetes, type 2 diabetes andother life-threatening diseases and guided by a compassionate, patient-centeredphilosophy.
City of Hope has one of the most influential type 1 and type 2 diabetesresearch programs in the world. Our scientists’ work has revolutionized theunderstanding and treatment of the disease and continues today with excitingdevelopments in cell transplantation, gene regulation, immune tolerance andgaining systemic understanding of diabetes as a complex, multifaceted disease.
To learn more about our exciting research and accomplishments inthe field of Diabetes, please visit https://www.cityofhope.org/research/diabetes-metabolism-research-institute
A Postdoctoral Fellow position is immediately availablein the laboratory of Dr. Ke Ma, Associate Professor, at the Diabetes and MetabolismResearch Institute within Beckman Research Institute of City of Hope, CA. TheMa lab applies state-of-the-art circadian biology, molecular and cellularbiology approaches to diabetes and obesity research, with a goal to unravelcircadian etiologies underlying the current epidemics of metabolic diseases fortargeted therapeutic interventions. We have a unique research program indeciphering the mechanistic underpinnings of circadian clock control inmetabolic tissue development, growth and functional capacity, specifically inskeletal muscle and adipose tissue.
We are seeking a highly motivated postdoctoralfellow with strong enthusiasm for metabolic disease or stem cell research to studymolecular signaling mechanisms underlying circadian clock function in skeletalmuscle and adipose tissue. Candidates with strong training in cell biology,molecular biology and biochemical techniques are preferred, and priorexperience with animal models is a plus. Utilizing biochemical and molecularbiology approaches combined with genetic animal models, specific researchdirections in the lab include: 1) genetic and epigenetic signaling networksmediating circadian clock nutrient-sensing function in adipose tissue andskeletal muscle; 2) circadian clock regulation of skeletal muscle growth and metabolism;and 3) novel signaling mechanisms in core circadian clock regulation.
Thecandidate should be self-motivated, with a proven track record of publicationsand strong interest to pursue metabolic disease research. Expertise in biochemistry,cell biology and animal physiology are preferred. Technical skills in metabolic,epigenetics and stem cell research are a plus.
Basic education, experience and skills required for consideration:
- PhD in Molecular, Cellular or Developmental Biology.
- Proficiency with biochemical techniques, molecular biology skills and cell culture systems.
- Experience with in vivo animal model research preferred.
- Experience with epigenetics research and bioinformatics analysis a plus.
- Highly motivated with strong interest in metabolic disease research.
- Strong work ethic and ability to work effectively in a team.
- For more information on Dr. Ke Ma please visit, here
- For a list of lab publications please visit, here
- To apply, please provide your current CV, a brief research statement describing your background, experiences and career goals, and a list of three references
- To protect the health of patients and staff and to comply with new State of California mandates, City of Hope staff are required to show proof of full vaccination by September 30, 2021. Compliance is a condition of employment.
City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.
City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.