Job Description

The Lu’s Laboratory in the Division of Nephrology, the Department of Medicine of MGH and Harvard Medical School has two openings for highly motivated postdoctoral fellows to study mechanisms of acute kidney injury and fluid and electrolytes imbalance disorders.

Dr. Lu’s lab is focusing on 1) studying integrin-extracellular matrix (ECM) signaling in kidney inflammation and interstitial fibrosis, and the mechanisms of survival, remodeling and regeneration of renal tubular cells after acute kidney injury, 2) understanding how ECM signaling contributes to the function and structural integrity of the kidney filtration barrier, and 3) how ECM signaling regulates the trafficking of membrane transporters such as water channel, aquaporins. There are multiple additional very exciting projects such as studying vascular calcification in kidney diseases, cardiorenal syndrome and renal inflammation that are also available depending on the experience and interest of the candidate.

Dr. Lu’s lab uses regular and 3-dimensional cell culture, organ culture and various tissue injury and transgenic mouse models, and applies comprehensive biochemical, cell biology and molecular approaches and state of the art imaging technology to interrogate mechanism of protein trafficking, cell death and regeneration during tissue injury and repair. Candidates will have ample opportunities to acquire and develop new skills, work closely with the PI and collaborators while working in a supportive, highly collaborative, and energetic environment. State-of-the-art facilities are available within an exceptional research setting. We are a results-oriented group of highly motivated scientists who perform basic and translational research on kidney diseases. At every level, we value intelligence, teamwork, dedication and creativity, and we’re always looking for people with those skills who thrive in teams and dynamic environments.

The candidates should hold a PhD or/and MD degree within biology, cellular, molecular biology, biochemistry, immunology and/or physiology. Experience with cell culture, basic biochemical techniques, immunocytochemistry or immunological technology is essential. Experience with animal study is an advantage. The position is open immediately although the start date is flexible. If interested, please submit CV to Dr. Lu (halu@partners.org)