Job Description

About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.
Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation’s leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary
The Postdoctoral Fellow position is available immediately in the Department of Immuno-Oncology at Beckman Research Institute in City of Hope Comprehensive Cancer Center, to explore mechanism of immune evasion in solid tumors and to develop novel immunotherapeutic strategies. We seek applications from candidates with proven experience in tumor immunology and cancer immunotherapy, with strong interests in translational research in animal models of human malignancies and/or in clinical studies. The environment of Beckman Research Institute is highly interactive and these projects will involve multiple collaborations across our Institution.

Key Responsibilities include:

• The ideal candidate will be able to work independently on molecular and cellular mechanisms of immunosuppression in humanized and syngeneic mouse models of solid tumors, including prostate cancers, utilizing the original oligonucleotide-based strategies for targeting tumor-associated myeloid cells.
• They will also participate in the ongoing clinical translation of the immunogenic CpG-STAT3 inhibitors to cancer immunotherapy.
• They will be responsible for drafting manuscripts, progress reports and presenting the results internally as well as extramurally when needed. The salary will commensurate with experience, with a possibility for promotion to more senior position.

For more information about the laboratory, please contact mkortylewski@coh.org , see our publications (e.g. Nature Med. 2018, Clin. Cancer Res. 2018; Mol. Ther. 2018, Blood 2016; Nature Biotechnol. 2009) and the following link: https://www.linkedin.com/in/marcin-kortylewski-6841b220/

Qualifications
Basic education, experience and skills required for consideration:

• Ph.D or similar doctoral degree.
• Skills in multicolor flow cytometry, immune assays and/or animal studies are an advantage.
• Highly motivated individuals with strong communication skills and ability to work in high paced, multidisciplinary environment are invited to apply.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.