Postdoctoral Fellow - Epigenetic Regulation of Pancreatic Beta-Cell Mass in Diabetes
- City of Hope
- Location: Duarte, CA
- Job Number: 7073374 (Ref #: 10008893)
- Posting Date: Dec 19, 2020
- Application Deadline: Open Until Filled
Job DescriptionAbout City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6,000 employees, is dedicated to the prevention and cure of cancer, type 1 diabetes, type 2 diabetes and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.
City of Hope has one of the most influential type 1 and type 2 diabetes research programs in the world. Our scientists’ work has revolutionized the understanding and treatment of the disease and continues today with exciting developments in cell transplantation, gene regulation, immune tolerance and gaining systemic understanding of diabetes as a complex, multifaceted disease.
To learn more about our exciting research and accomplishments in the field of Diabetes, please visit https://www.cityofhope.org/research/diabetes-metabolism-research-institute
A Postdoctoral Fellow position is available in the laboratory of Dr. Sangeeta Dhawan, at the Diabetes and Metabolism Research Institute at City of Hope. We are looking for a highly motivated postdoctoral fellow interested in studying the epigenetic regulation of pancreatic beta-cell mass in health and diabetes. In addition, our lab is interested in the dynamics of beta-cell diversity, islet organization and cell-cell interaction in fetal and neonatal development. The Dhawan lab utilizes genetic mouse models, molecular biology and epigenetic techniques to study the cellular identity, function, remodeling, and survival of beta-cells in physiological and pathological conditions.
The ideal candidate will have extensive experience in molecular biology and rodent models. Experience with epigenetic techniques preferred. The candidate should be self-motivated, with a proven track record of productivity.
Basic education, experience and skills required for consideration:
- PhD in Molecular, Cellular or Developmental Biology.
- Strong interest in diabetes research.
- Extensive experience with basic molecular biology skills.
- Extensive experience in handling animal models.
- Experience with tissue collection, histology, immunohistochemistry, and cell sorting.
- Experience with cell culture, immunofluorescence, and flow cytometry.
- Experience with epigenetic techniques preferred.
- Strong work ethic, meticulous and detail-oriented record keeping habits.
- Excellent written and verbal communication skills. Evidence of productivity reflected in first author publications in peer-reviewed journals.
- Good problem-solving skills and passion to follow relevant literature.
- Ability to conduct independent research, and work effectively in a team.
- Willingness to apply for fellowships and training grants.
- For more information on Dr. Sangeeta Dhawan’s research please visit, here
- To apply, please provide your current CV and a list of three references
City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.
City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.