Postdoctoral Fellow - Diabetes Complications and Metabolism
- City of Hope
- Location: Duarte, CA
- Job Number: 7071815 (Ref #: 10008402)
- Posting Date: Nov 5, 2020
- Application Deadline: Open Until Filled
Job DescriptionAbout City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6,000 employees, is dedicated to the prevention and cure of cancer, type 1 diabetes, type 2 diabetes and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.
City of Hope has one of the most influential type 1 and type 2 diabetes research programs in the world. Our scientists’ work has revolutionized the understanding and treatment of the disease and continues today with exciting developments in cell transplantation, gene regulation, immune tolerance and gaining systemic understanding of diabetes as a complex, multifaceted disease.
To learn more about our exciting research and accomplishments in the field of Diabetes, please visit https://www.cityofhope.org/research/diabetes-metabolism-research-institute
A Postdoctoral Fellow position is immediately available in the laboratory of Dr. Ke Ma, Associate Professor, at the Diabetes and Metabolism Research Institute within Beckman Research Institute of City of Hope, CA. The Ma lab applies state-of-the-art circadian biology, molecular and cellular biology approaches to diabetes and obesity research, with a goal to unravel circadian etiologies underlying the current epidemics of metabolic diseases for targeted therapeutic interventions. We have a unique research program in deciphering the mechanistic underpinnings of circadian clock control in metabolic tissue development, growth and functional capacity, specifically in skeletal muscle and adipose tissue.
We are seeking a highly motivated postdoctoral fellow with strong enthusiasm for metabolic disease or stem cell research to study molecular signaling mechanisms underlying circadian clock function in skeletal muscle and adipose tissue. Candidates with strong training in cell biology, molecular biology and biochemical techniques are preferred, and prior experience with animal models is a plus. Utilizing biochemical and molecular biology approaches combined with genetic animal models, specific research directions in the lab include: 1) genetic and epigenetic signaling networks mediating circadian clock nutrient-sensing function in adipose tissue and skeletal muscle; 2) circadian clock regulation of skeletal muscle growth and metabolism; and 3) novel signaling mechanisms in core circadian clock regulation.
The candidate should be self-motivated, with a proven track record of publications and strong interest to pursue metabolic disease research. Expertise in biochemistry, cell biology and animal physiology are preferred. Technical skills in metabolic, epigenetics and stem cell research are a plus.
Basic education, experience and skills required for consideration:
- PhD in Molecular, Cellular or Developmental Biology.
- Proficiency with biochemical techniques, molecular biology skills and cell culture systems.
- Experience with in vivo animal model research preferred.
- Experience with epigenetics research and bioinformatics analysis a plus.
- Highly motivated with strong interest in metabolic disease research.
- Strong work ethic and ability to work effectively in a team.
- For more information on Dr. Ke Ma please visit, here
- For a list of lab publications please visit, here
- To apply, please provide your current CV, a brief research statement describing your background, experiences and career goals, and a list of three references
City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.