Postdoctoral Fellow (Cancer Biology w/ Dr. Shabnam Shalapour)
- The University of Texas MD Anderson Cancer Center
- Location: Houston, TX
- Job Number: 7070695
- Posting Date: Oct 7, 2020
- Application Deadline: Open Until Filled
Job DescriptionA postdoctoral fellow position is available in the Department of Cancer Biology under the direct supervision of Dr. Shabnam Shalapour. Research in the Shalapour Laboratory focuses on the role of chronic inflammation and adaptive immunity in control of tumor development and the response of various cancers to therapy. While the focus of the research is primarily based on tumor immunology and immunotherapy, our work also addresses fundamental questions in immunology, immunometabolism and cancer biology using cutting-edge technology tools including multicolor Flow cytometry, CyTOF, imaging, histology and large-scale omic analysis, e.g. single-cell RNA and ATAC-seq . We aim to understand how chronic inflammation induced by obesity, aging and alcohol abuse affect the immune system and thereby regulates its response to pathogens (bacteria and virus) and support tumor development. The focus then being how to use this information to not only prevent cancer development but also to develop novel therapeutic approaches to increase the response to immunotherapy and vaccination (see our recent publications; Nature. 2015 May 7;521(7550):94-8, J Clin Invest. 2015 Sep;125(9), Nature. 2017 Nov 16;551(7680):340-345.; Immunity. 2019 Jul 16;51(1):15-26, Annu Rev Immunol. 2020 Apr 26;38:649-671).
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