Postdoc Fellow, Circadian Clock Control in Metabolic Tissue Development
- City of Hope
- Location: Duarte, CA
- Job Number: 7067412 (Ref #: 10004551rxv_26_1)
- Posting Date: Jul 2, 2020
- Application Deadline: Open Until Filled
Job DescriptionThank you for your interest. Please note, the purpose of this posting is to recruit for on-going and future positions in the Diabetes and Metabolism Research Institute laboratory of Dr. Ke Ma which investigates signaling mechanisms underlying circadian clock control in metabolic tissue development, growth and functional capacity.
About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.
Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation’s leading cancer centers that develops and institutes standards of care for cancer treatment.
A Postdoctoral Fellow position is available in the laboratory of Dr. Ke Ma, Associate Professor, at the Diabetes and Metabolism Research Institute within Beckman Research Institute of City of Hope. The Ma lab applies state-of-the-art circadian biology, molecular and cellular biology approaches to diabetes and obesity research, and we have established a unique program in deciphering the signaling mechanisms underlying circadian clock control in metabolic tissue development, growth and functional capacity.
We are looking for a highly motivated postdoctoral fellow with strong enthusiasm for metabolic disease or stem cell research to discover novel epigenetic mechanisms mediating circadian clock functions in adipose depots and skeletal muscle. Ultimately, our goal is to unravel circadian etiologies underlying the current epidemics of metabolic diseases for targeted therapeutic interventions. Utilizing biochemical and molecular biology approaches combined with animal physiology in genetic mouse models, the specific research directions in Ma Lab will explore, 1) epigenetic networks mediating clock nutrient-sensing function in adipose tissue and skeletal muscle; 2) circadian clock regulation of stem cell behavior in skeletal muscle development, growth, and regeneration; and 3) novel roles of circadian regulators in cancer development and metabolism.
The candidate should be self-motivated, with a proven track record of productivity and strong interest in metabolic disease, epigenetics or stem cell research.
Basic education, experience and skills required for consideration:
- PhD in Molecular, Cellular or Developmental Biology;
- Proficiency with biochemical techniques, molecular biology skills and cell culture systems;
- Highly motivated with strong interest in metabolic disease research;
- Strong work ethic and ability to work effectively in a team.
- Experience with in vivo animal model research;
- Experience in biochemistry and gene regulation;
- Experience with epigenetics research and genomic bioinformatics analysis;
- Technical skills in metabolic, epigenetics, and stem cell research.
- For more information about Dr. Ma’s lab, please click here;
- To apply, please provide your CV, a brief research statement and a list of three references.
City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.