Date Posted: May 22, 2019
The Poché Lab seeks a highly motivated postdoctoral research associate/fellow with experience in mouse retinal developmental biology, regeneration, and transcriptome analysis. This position is focused on the study of the molecular mechanisms blocking mammalian Müller glial cell (MG)-mediated retinal regeneration. Our long-term goal is to determine whether the mouse retina retains latent regenerative potential akin to other vertebrates such as the zebrafish and whether we can genetically "awaken" that potential to restore sight.
Special emphasis will be placed on the investigation of MG transcriptional reprogramming to a progenitor-like state. Preference will be given to candidates with a strong background in mouse genetics and in techniques to probe the retinal transcriptome and epigenome. This expertise should ideally include next gen sequencing (RNA-seq, ChIP-seq, ATAC-seq, single cell-seq, etc.) data analysis.
The Poché lab employs a multi-disciplinary approach utilizing genetic loss- and gain-of-function experiments, fate mapping, gene therapy, molecular biology, and live retinal confocal microscopy. We are housed in the Department of Molecular Physiology and Biophysics at Baylor College of Medicine (BCM). Located in the Texas Medical Center, the largest medical center on the world, BCM postdocs have a tremendous amount of technical and intellectual resources at their disposal.
In your application, please include a cover letter, current CV, and contact information for three references. Review of applications will begin immediately and will continue until the position is filled. Please contact Dr. Poché at firstname.lastname@example.org.