- Albert Einstein College of Medicine
- Location: Bronx, NY
- Job Number: 7102714
- Posting Date: Jun 16, 2022
Albert Einstein College of Medicine, a part of Montefiore, is a premier, research-intensive medical school dedicated to innovative biomedical investigation and to the development of ethical and compassionate physicians and scientists. Inspired by the words of our namesake, we have from our inception welcomed students, faculty and staff from diverse backgrounds who strive to enhance human health in the community and beyond. This is an attribute in which Albert Einstein took great pride when consenting to the use of his name in conjunction with the medical school.
At the core of the Einstein-Montefiore mission is the pursuit of social justice in meeting the healthcare needs of all individuals, including those from underserved communities.
While education is at the heart of Einstein's mission, it is biomedical research that drives the College of Medicine's growth. Einstein has more than 1,952 full-time faculty members located on its Jack and Pearl Resnick campus, and at Montefiore and its other clinical affiliates.
Einstein's relationship with Montefiore supports a longstanding focus on bench-to-bedside research, through which discoveries in Einstein's laboratories lead to therapies and treatments for patients on an accelerated timetable.
The laboratory of Dr. David Loeb (https://www.cham.org/patients-families/find-a-doctor/david-m-loeb-mdphd-1841236676) in the Department of Developmental and Molecular Biology and the Department of Pediatrics is seeking to fill an NIH-funded post-doctoral position immediately. We are searching for a creative, independent, and energetic person for a post-doctoral position to study how modulating Wnt signaling can inhibit osteosarcoma metastasis. Using a clinically relevant mouse model of osteosarcoma metastasis, our laboratory discovered that a neutralizing antibody against the canonical Wnt signaling antagonist, DKK-1, abolishes metastasis. The current project is investigating the molecular details of the effect of DKK-1 on both canonical and noncanonical Wnt signaling as well as using preclinical modeling to optimize the integration of DKK-1 inhibition with chemotherapy.
The project requires the use and development of transgenic mouse models, surgical technique for orthotopic models, and multiplex immunofluorescence techniques, as well as standard molecular biology techniques. Applicants must 1) already have, or be about to have, successfully completed a PhD in a relevant field (e.g. cancer biology, molecular biology, etc.); 2) have experience in cell culture; 3) have some experience in microscopy and image analysis; and 4) be willing to work with live mice. An applicant must be strong in troubleshooting and experimental design and have publications illustrating such expertise.
To apply, applicants must submit: 1) A cover letter describing the applicant's interest in the position; 2) A curriculum vitae; and 3) Three letters of reference. Email applications with the subject “PDAC Post Doc” to David Loeb ([email protected]).
Applications must be complete (with items 1-3 above).
The starting salary is competitive and depends on experience at time of arrival.
The Albert Einstein College of Medicine is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information. Einstein seeks candidates whose skills, and personal and professional experience, have prepared them to contribute to our commitment to diversity and excellence, and the communities we serve.