Postdoctoral Fellow - Epigenetic Regulation of Pancreatic Beta-cell Mass
- City of Hope
- Location: Duarte, CA
- Job Number: 7096608 (Ref #: 10015820)
- Posting Date: Apr 26, 2022
- Application Deadline: Open Until Filled
About City of Hope
City of Hope is an independent biomedical research and treatment organization for cancer, diabetes and other life-threatening diseases.
Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope™, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hope’s specialized cancer expertise.
A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.
City of Hope’s commitment to Diversity, Equity and Inclusion
We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all of our communities. Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds and experiences to our work -- and that our teams align with the people we serve in order to build trust and understanding. We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds and perspectives; this is reflected in our work and represented in our people.
Position Summary and Key Responsibilities
A Postdoctoral Fellow position is available in the laboratory of Dr. Sangeeta Dhawan, at the Diabetes and Metabolism Research Institute at City of Hope. We are looking for a postdoctoral fellow interested in studying the epigenetic regulation of pancreatic beta-cell mass in health and diabetes. In addition, our lab is interested in the dynamics of beta-cell diversity, islet organization and cell-cell interaction in fetal and neonatal development. The Dhawan lab utilizes genetic mouse models, molecular biology and epigenetic techniques to study the cellular identity, function, remodeling, and survival of beta-cells in physiological and pathological conditions.
The ideal candidate will be full of curiosity and enthusiasm and have extensive experience in molecular biology and rodent models. Experience with epigenetic techniques preferred. The candidate should be self-motivated, with a proven track record of productivity.
To apply, please provide your CV and a list of three references.
Basic Education and Skills Required for Consideration:
- PhD in Molecular, Cellular or Developmental Biology.
- Strong interest in diabetes research.
- Extensive experience with basic molecular biology skills.
- Extensive experience in handling animal models.
- Experience with tissue collection, histology, immunohistochemistry, and cell sorting.
- Experience with cell culture, immunofluorescence, and flow cytometry.
- Experience with epigenetic techniques preferred.
- Strong work ethic, meticulous and detail-oriented record keeping habits.
- Excellent written and verbal communication skills. Evidence of productivity reflected in first author publications in peer-reviewed journals.
- Good problem-solving skills and passion to follow relevant literature.
- Ability to conduct independent research and work effectively in a team.
- Willingness to apply for fellowships and training grants.
- As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.
City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.
City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.