Postdoctoral Research Fellow
- New York Blood Center
- Location: New York, NY
- Job Number: 7091099
- Posting Date: Dec 27, 2021
Job DescriptionAt New York Blood Center, one of the most comprehensive blood centers in the world, our focus is on cultivating excellence by merging cutting-edge innovation with diligent customer service, groundbreaking research, and comprehensive program and service development. Join us as we work towards meeting and exceeding the growing needs of our diverse communities, further our lifesaving strategic goals in a rapidly changing environment, and expand our impact on the local, national, and global communities we serve.
This position is responsible for conducting immunological studies in vitro and using vaccine models in mice. This role will work to support the development of rOv-ASP-1, a novel adjuvant for human use. It will establish the mechanisms by which it exerts its activity and substantiate its potential use as an immunomodulators using SARS model and other vaccine models such as influenza
Conduct and design independent research under the direction of lab Principal Investigator (PI).
Culture of human and mouse cells: Set tissue cultures using defined cells to detect and analyze responses to external stimuli.
Study the function of a Parasite derived proteins: Test the bioactivities of the recombinant adjuvant using suitable in vitro and in vivo assays.
Immunize mice and test the innate and adaptive responses induced:
Inject mice, collect blood and tissues and analyze the immune responses induced ex vivo to vaccine antigens and external stimuli by ELISA and FACS analyses and using other developed assays such as testing for presence and titer of neutralizing/killing antibodies.
Develop protocols, execute them and solve problems if needed Independence, productively and creativity.
Discuss protocols, experiment, outcomes, and future plans.
Good communicating skills, record maintenance and paying attention to details.
5 plus years of broad knowledge and experience in (human and mouse) cellular and humoral immunity
Knowledge of Molecular biology techniques including PCR analysis
Knowledge in cellular and molecular immunological techniques
Knowledge of general immunological techniques are required in particular tissue culture, ELISA, cytokine assays, FACS analysis, handling of mice (including immunization, bleeding and removing organs), vaccinology as well as some aspects of molecular biology.
Knowledge of a variety of software applications (Microsoft Office Suite) including Prism.