Postdoctoral Research Fellow
- Memorial Sloan Kettering Cancer Center
- Location: NY
- Job Number: 7071181
- Posting Date: Oct 21, 2020
- Application Deadline: Open Until Filled
Job DescriptionMemorial Sloan Kettering Cancer Center (MSK) is one of the world’s premier cancer centers, committed to exceptional patient care, leading-edge research, and superb educational programs. The blending of research with patient care is at the heart of everything we do. The institution is a comprehensive cancer center whose purposes are the treatment and control of cancer, the advancement of biomedical knowledge through laboratory and clinical research, and the training of scientists, physicians and other health care workers.
Benjamin Nacev, MD PhD (https://www.mskcc.org/cancer-care/doctors/benjamin-nacev) is seeking a highly motivated and successful individual who will work with him both at MSK and in the sarcoma subgroup of the Laboratory of Chromatin Biology and Epigenetics (http://lab.rockefeller.edu/allis/), which is headed by C. David Allis PhD and located at our Tri-institutional partner, The Rockefeller University.
Epigenetic regulation controls many important biologic processes and occurs through multiple mechanisms including DNA methylation, the regulation of the complex of DNA and associated proteins called chromatin, and three-dimensional genome architecture. Genes that are important for epigenetic regulation are often altered in cancer with deleterious effects, but the mechanism of these effects and even the genes involved are not fully understood. The applicant will participate in a cutting-edge research program designed to understand how genetic alterations in epigenetic regulators lead to the development of sarcomas, with a goal of designing better cancer treatments for this group of rare cancers. The work will leverage unique resources of patient-derived cell lines and xenografts as well as targeted sequencing data from a large cohort of sarcoma patients.
We are looking for a self-motivated, inquisitive, ambitious, and enthusiastic postdoctoral fellow (PhD or MD/PhD; PGY 0-2) who has a thirst for scientific knowledge and discovery, thrives in a fast-paced environment, takes independent initiative to adopt and optimize new techniques, and works well as part of a team. The ideal candidate will have a background in genetics, epigenetics, and/or cancer biology and will have a familiarity with molecular and genetic approaches, methods, and data analysis. The applicant should be seeking a 3-year commitment. The candidate should be willing to work with human tissue samples and cell lines and mouse models.
Responsibilities will include working with Dr. Nacev to design and execute bench experiments, coordinating work with Tri-Institutional collaborative laboratories and cores, and keeping detailed laboratory records. In addition, applicant will analyze results to derive robust conclusions, design follow-up experiments, and prepare manuscripts and presentations pertaining to the work.
To apply, please send your CV, statement of research interests, and names of three references to Britny James (firstname.lastname@example.org).
MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.
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