Post Doctoral Associate
- University of Minnesota
- Location: Minneapolis, MN
- Job Number: 7058782
- Posting Date: Jul 30, 2019
- Application Deadline: Open Until Filled
Job DescriptionTitle: Post Doctoral Associate Analytical and Bioanalytical Chemist
About the Job: An experienced analytical mass spectrometrist is sought to develop and validate biomarkers of exposures to environmental and dietary carcinogens, and their DNA adducts in cells and human tissues. The research requires derivatization chemistry for tagging biomarkers to enhance analyte detection by LC/MS or GC/MS and mass spectrometric characterization of biomarkers in complex biological matrices. The candidate is expected to work semi-independently in LC/MS development and validation of DNA adduct biomarkers employing triple quadrupole, ion trap and high resolution MS instruments, and GC/MS to measure volatile toxicants in tobacco smoke.
•Doctoral Degree-required, preferred field of study analytical science, biology, biochemistry, chemistry, or related field
•Experience with Mass Spectrometry instrumentation; GC-MS and/ or LCMS-MS and chemical derivatization
•Extensive experience on operating and maintaining different mass spec instruments and data analysis software
•This candidate should have a working knowledge of qualitative and quantitative analysis of biomarkers, trace-level analysis of biomolecules in vivo, and cell culture experience is preferred
•Excellent written and oral communication skills.
•Strong computer skills and experience in generating graphical outputs of data for reports and publications
•The candidate must be organized and work diligently to meet timelines.
About the Lab: Our research is focused on the biochemical toxicology of dietary and environmental genotoxicants, as well as endogenous electrophiles that damage protein and DNA. Our long-term objectives are to understand the etiological roles of t chemicals, and implement chemical markers and state-of-the-art mass spectrometry methods for use in molecular epidemiology studies that seek to understand the origin of human cancer for which an environmental cause is suspected.